Nā huahana

ʻO 1-(4-Nitrophenyl)piperazine, ʻike ʻia hoʻi ʻo 4-Nitro-1-phenylpiperazine, he mea hoʻohui kemika e paʻa ana i ke koʻikoʻi i nā ʻano ʻepekema ʻano like ʻole, ma mua o ka lāʻau lapaʻau a me ka noiʻi lāʻau lapaʻau. ʻO -Nitrophenyl)piperazine kona hoʻohana ʻana ma ke ʻano he waena i ka synthesis o nā pūhui bioactive like ʻole.Ke hana nei kēia pūhui ma ke ʻano he hale kūkulu hale no ka hana ʻana i nā lāʻau lapaʻau i hoʻohana ʻia no ka huli ʻana i nā wahi therapeutic kikoʻī, e like me nā maʻi o ka ʻōnaehana nerve waena, ka maʻi kanesa, a me nā maʻi maʻi.ʻO ka loaʻa ʻana o nā hui piperazine a me nitrophenyl i loko o kona ʻano e hoʻomaʻamaʻa i ka hana ʻana i nā molekala paʻakikī ma o ka hoʻopili ʻana i kahi ʻano o nā hui hana, e alakaʻi ana i nā pūhui me nā hana biological i hoʻonui ʻia a hoʻomaikaʻi ʻia nā waiwai lāʻau lapaʻau. ʻo ia ke kumuhana o nā haʻawina lāʻau lapaʻau, pili pono i kona hopena i ka ʻōnaehana nerve waena.Ua ʻike ʻia ka pūhui e launa pū me nā mea loaʻa neurotransmitter like ʻole, me ka dopamine a me ka serotonin receptors.Ua hoʻoikaika kēia mau pilina i ka noiʻi ʻana i kona hiki ke ʻano he psychoactive agent, a me kona hiki i ka mālama ʻana i nā maʻi psychiatric. kahua ʻepekema.No ka laʻana, ua hōʻike ʻo ia i ka pono ma ke ʻano he ligand i ke kemika hoʻonohonoho, hiki ke hoʻokumu i nā paʻakikī metala me nā ion metala like ʻole.He mea hoihoi kēia mau paʻakikī no ko lākou hiki i ka catalytic reactions a me ka ʻepekema waiwai.ʻO ka ʻike piha o nā pepa ʻikepili palekana, ka mālama ʻana i nā alakaʻi palekana, a me ka hoʻohana ʻana i nā lako pale pono e pono ai no ka mālama pono ʻana i kēia pūhui. kemika, hoʻomaʻamaʻa i ka synthesis o nā pūhui bioactive me nā noi lapaʻau kūpono.Ua loaʻa pū ʻo ia i ka nānā ʻepekema ma muli o kāna mau hana lāʻau lapaʻau a me ka launa pū ʻana me nā neurotransmitter receptors.Hoʻohui ʻia, hoʻohui kona waiwai ma ke ʻano he ligand i ka kemika hoʻohui i kona waiwai ma nā wahi noiʻi like ʻole.Eia nō naʻe, pono e mālama ʻia nā pale palekana i ka wā e hana pū ai me kēia pūhui e hōʻoia i ka mālama pono ʻana a e hōʻemi i nā pilikia.