Nā huahana

ʻO 1-Boc-piperazine, ka mea i kapa ʻia ʻo N-Boc-piperazine a i ʻole tert-butoxycarbonyl-piperazine, he mea hoʻohui kemika i hoʻohana nui ʻia i nā kula o ka lāʻau lapaʻau a me ka synthesis organik.Hōʻike ʻia ka pūhui me ka loaʻa ʻana o kahi hui pale tert-butoxycarbonyl (Boc) ma ke apo piperazine.ʻO kekahi o ka hoʻohana mua ʻana o 1-Boc-piperazine he hui pale i ka synthesis organik.Hāʻawi ka hui Boc i ka pale no ka manawa pōkole no nā hana amine i ka wā o nā hopena kemika, e pale ana i nā hopena ʻaoʻao makemake ʻole a i ʻole nā ​​hopena makemake ʻole me nā reagents ʻē aʻe.Ma hope o ka hoʻololi ʻana o ka kemika i makemake ʻia, hiki ke hoʻoneʻe ʻia ka hui Boc ma lalo o nā kūlana hoʻohālikelike kikoʻī, e hōʻike ana i ka amine manuahi.Hoʻohana maʻamau ʻia kēia hoʻolālā i ka synthesis o nā pūhui lāʻau lapaʻau like ʻole, e ʻae ana i ka hoʻomalu pololei ʻana i nā hopena hopena a me ka pale ʻana i nā hui amine koʻikoʻi.Ma ka noiʻi lāʻau lapaʻau a me ka hoʻomohala ʻana i ka lāʻau lapaʻau, lawelawe ʻo 1-Boc-piperazine ma ke ʻano he hale kūkulu koʻikoʻi no ka synthesis o nā molekole bioactive like ʻole.Hiki ke hoʻohana ʻia ma ke ʻano he mea waena e synthesize i kahi ākea o nā lāʻau lapaʻau, me ka ʻaʻole i kaupalena ʻia i nā antidepressants, antipsychotics, anticonvulsants, a me nā lāʻau antiviral.ʻO kona hiki ke hoʻolauna i nā hana kikoʻī a me nā pūʻulu palekana ma ke apo piperazine e lilo ia i mea waiwai nui no nā mea lapaʻau lapaʻau i ka hoʻolālā ʻana a me ka synthesizing i nā moho lāʻau lapaʻau.Eia kekahi, ua noiʻi ʻia ʻo 1-Boc-piperazine no kāna hiki therapeutic.Ua ʻimi kekahi mau haʻawina i kāna mau hana lāʻau lapaʻau, e komo pū ana me nā mea hoʻokipa neurotransmitter.Ua alakaʻi kēia i nā noiʻi i kona hiki ke hoʻohana ʻia ma ke ʻano he lāʻau lapaʻau no nā ʻano maʻi ʻōnaehana kikowaena waena, e like me ka hopohopo a me ke kaumaha.Eia naʻe, he mea nui e hoʻomaopopo he pono ka noiʻi hou e hoʻomaopopo pono a hōʻoia i kāna mau noi therapeutic.I ka lawelawe ʻana i ka 1-Boc-piperazine a i ʻole ka hana ʻana me nā pūhui i loaʻa kēia ʻāpana, pono e hahai i nā kuʻina palekana kūpono.Manaʻo ʻia e nīnau i nā pepa ʻikepili palekana a mālama i nā hana lab kūpono a me nā hana pale.Eia hou, pono e hahai ʻia nā ʻōlelo kuhikuhi no ka mālama pono ʻana a me ka hoʻokuʻu ʻana e hōʻoia i ka mālama pono ʻana a me ka mālama ʻana i kēia pūhui.I ka hōʻuluʻulu ʻana, ʻo 1-Boc-piperazine kahi hui koʻikoʻi i ka synthesis organik a me ka noiʻi lāʻau lapaʻau.ʻO kona hoʻohana ʻana ma ke ʻano he pūʻulu pale e hiki ai ke kaohi pololei ʻana i nā hopena kemika, ʻoiai ʻo kāna hana ma ke ʻano he waena e hiki ai i ka synthesis o nā molekole bioactive like ʻole.Hoʻohui ʻia, ʻo nā noiʻi ʻana i kona hiki ke hōʻike i kona hiki ke loaʻa a me ka hoʻomohala ʻana i ka lāʻau.Eia naʻe, pono e mālama i ka mālama ʻana i kēia pūhui e hōʻoia i ka palekana a me ka hoʻokō ʻana i nā protocol i hoʻopaʻa ʻia.