Nā huahana

ʻO ka 1-Methyl-4-pyrazole boronic acid pinacol ester he mea hoʻohui me ka laulā o nā noi, ʻoi aku ka nui o ke ʻano o ka synthesis organik.ʻO kona ʻano kū hoʻokahi a me ka hoʻoulu ʻana e lilo ia i mea waiwai i nā hopena kemika like ʻole a ma ke ʻano he hale kūkulu no ka synthesis o nā molekala paʻakikī. nā paʻa kalapona-heteroatom.Hiki i ka hui waika boronic i loko o ka mole ke komo i nā ʻano hoʻohui cross-coupling Suzuki-Miyaura, e hiki ai ke hoʻopili i ka moiety 1-methyl-4-pyrazole i nā pūhui ʻē aʻe a i ʻole nā ​​​​hui hana.ʻO kēia hopena e hiki ai i nā mea kemika ke hana i nā pūhui organik paʻakikī me nā hale a me nā waiwai.Hiki ke wehe maʻalahi kēia pūʻulu pale ma lalo o nā kūlana haʻahaʻa, e hōʻike ana i ka hui waika boronic no nā hoʻololi hou.No laila, lawelawe ʻo 1-Methyl-4-pyrazole boronic acid pinacol ester ma ke ʻano he versatile intermediate i ka synthesis o pharmaceuticals, agrochemicals, a me nā kemika maikaʻi ʻē aʻe. nā moho lāʻau lapaʻau.Ma ka hoʻohana ʻana i ka 1-Methyl-4-pyrazole boronic acid pinacol ester ma ke ʻano he mea hoʻomaka, hiki i nā mea kemika ke hoʻokomo i ka moiety 1-methyl-4-pyrazole i loko o kahi mole i hoʻopaʻa ʻia, e hāʻawi ana i nā hiʻohiʻona kikoʻī a i ʻole nā ​​​​hana.Hiki i nā pūhui hopena ke hōʻike i ka hoʻoikaika ʻana i ka hana biological, hoʻomaikaʻi i ka pharmacokinetics, a i ʻole ka hōʻemi ʻana i ka ʻona.Hiki iā ia ke lilo i ligand, hui pū me nā mea hoʻoheheʻe metala a komo i nā hopena catalytic like ʻole.Hiki i ka hui waika boronic o kēia pūhui ke hana i nā mea paʻakikī me nā metala hoʻololi, e ʻae ana i ka hoʻāla ʻana o nā paʻa CH a i ʻole ka catalysis o nā hopena hoʻohui keʻa.Hoʻohana ʻia kēia mau waiwai no ka synthesis o nā mea hana a i ʻole ke kūkulu ʻana i nā ʻōnaehana catalytic hou. hoʻopalekana.ʻO kāna hana waika boronic a me ka hui pinacol ester he mea pono ia no ka hoʻokumu ʻana i nā hopena paʻa carbon-carbon a i ʻole carbon-heteroatom bond, e hiki ai ke hana i nā molekala paʻakikī.Hoʻopili kāna mau noi i nā ʻoihana like ʻole, me ka synthesis o nā lāʻau lapaʻau, ka hoʻomohala ʻana i nā mea hana, a me ka holomua o nā ʻōnaehana catalytic.ʻO ka versatility a me ka reactivity o 1-Methyl-4-pyrazole boronic acid pinacol ester e lilo ia i mea hana waiwai no nā mea kemika e hana ana i ka synthesis o nā pūhui hou a me ka hoʻolālā ʻana o nā hopena hou.