1,1-Cyclobutanedicarboxylatodiammineplatinum (II) Cas:41575-94-4
Helu Helu | XD90684 |
inoa mea kūʻai | 1,1-Cyclobutanedicarboxylatodiammineplatinum (II) |
CAS | 41575-94-4 |
ʻĀpana Molekala | C6H12N2O4Pt |
Kaumaha Molecular | 371.25 |
Nā kikoʻī mālama | 2-8°C |
Kānāwai Kūʻai Kūlike | 28439090 |
Huahana Huahana
Ka nana aku | ʻO ka pauka keʻokeʻo keʻokeʻo |
Hoʻāʻo | 99% |
Wai | ≤0.5% |
Nalo ma ka maloo | ≤0.5% |
Klorida | ≤100ppm |
Na mea pili | ≤0.25% |
ʻO nā mea haumia ʻole i hōʻike ʻia | ≤ 0.1% |
ʻO nā mea haumia ʻē aʻe a pau | ≤0.5% |
1,1-Cyclobutanedicarboxylic acid | ≤ 0.5% |
ʻO nā lāʻau antineoplastic paʻakikī o ka lua o ka hanauna.Ua like ka hana antitumor spectrum a me ka antitumor me ka cisplatin, akā ʻoi aku ka maikaʻi o ka hoʻoheheʻe wai ma mua o ka cisplatin, a ʻoi aku ka haʻahaʻa o ka ʻawaʻawa i ka puʻupaʻa.He maikaʻi curative ka hopena ma ka liʻiliʻi maʻi 'aʻai māmā, ovarian maʻi 'aʻai, poʻo a me ka 'ā'ī squamous cell carcinoma, testicular tumor, malignant lymphoma, etc. Hiki ke hoʻohana 'ia no ka cervical maʻi 'aʻai, maʻi 'aʻai, etc.
ʻO nā lāʻau lapaʻau platinum anticancer lua ka hana like a me ka hoʻohana ʻana e like me cisplatin.ʻOi aku ka ikaika ma mua o ka cisplatin no kekahi mau maʻi koko, a ʻoi aku ka ikaika ma mua o ka cisplatin ma ke ʻano he radiosensitizer ma lalo o nā kūlana hypoxic.Hoʻohana nui ʻia no ka maʻi maʻi ovarian, ka maʻi maʻi testicular, ka maʻi maʻi ʻāʻī liʻiliʻi a me ka maʻi maʻi poʻo a me ka ʻāʻī.
ʻO Carboplatin kahi lāʻau anticancer e pili ana i ka platinum e hoʻopōʻino i ka DNA ma o ka hana ʻana i ka conjugation intrachain i nā koena guanine e pili ana.Loaʻa ka hopena antitumor o kēia mau lāʻau ma muli o ka nalowale o ka hana DNA mismatch repair (MMR vaccine) a me ka hoʻokomo ʻana o ka make cell programmed.