Nā huahana

(1R,2S,5S)—6,6-DiMethyl-3-aza-bicylo[3.1.0]hexane-2-carboxylic acid ʻO Methyl ester hydrochloride kahi hui kemika me nā noi like ʻole i ka noiʻi lāʻau lapaʻau a me ka hoʻomohala lāʻau. ʻO ka hoʻohana nui ʻana o kēia pūhui ma ke ʻano he papa hale chiral i ka synthesis o nā mea waena lāʻau lapaʻau a me nā mea lāʻau lapaʻau ikaika (API).ʻO kāna ʻano bicyclic kūʻokoʻa a me ka chirality he mea waiwai ia i ka hana ʻana o nā pūhui enantiomerically maʻemaʻe.Ma ka hoʻokomo ʻana i kēia pūhui i loko o ka synthesis, hiki i nā chemists ke hoʻomalu i ka stereochemistry a hana i nā waiwai pharmacological kikoʻī i loko o nā molekele hopena.He mea koʻikoʻi kēia i ka hoʻomohala ʻana i ka lāʻau lapaʻau, kahi e hilinaʻi pinepine ai ka hana olaola i makemake ʻia i ka hoʻonohonoho ʻana o ka molekala. -2-carboxylic acid Methyl ester hydrochloride i hoʻohana ʻia ma ke ʻano he precursor no ka synthesis o nā lāʻau lapaʻau quinuclidine.Ua hōʻike ʻia nā derivatives Quinuclidine i ka nui o nā hana olaola, e komo pū me nā waiwai antipsychotic, anticonvulsant, a me analgesic.Ma ka hoʻokomo ʻana i nā pūʻulu hana kikoʻī i ka pūhui, hiki i nā chemists ke hoʻololi i kāna mau mea pharmacokinetic a me pharmacodynamic, hoʻonui i kona hiki ke hoʻōla.Ma muli o ka loaʻa ʻana o kahi amine tertiary a me ke ʻano o nā pūʻulu methyl, hiki iā ia ke komo i nā hopena kemika like ʻole, e like me ka amidation, alkylation, a me nā hopena cycloaddition.ʻO kāna hana a me kona hiki ke hana i nā mea waena paʻakikī e lilo ia i mea hana maʻalahi i ka synthesis organik, e ʻae ai i ka hana ʻana i nā pūhui like ʻole. .0]hexane-2-carboxylic acid ʻO Methyl ester hydrochloride kahi hui waiwai i ka hoʻomohala ʻana i ka lāʻau lapaʻau a me ka synthesis organik.ʻO kona chirality a me kona ʻano ʻokoʻa e hiki ai ke hana i nā pūhui enantiomerically pure a me ka synthesis o nā lāʻau lapaʻau quinuclidine me nā waiwai pharmacological kikoʻī.ʻO kona reactivity hoʻi e lilo ia i mea hoʻopiʻi pono a me ka catalyst i nā loli kemika like ʻole.Ma ke ʻano holoʻokoʻa, he hana koʻikoʻi kēia hui i ka holomua o ka noiʻi lāʻau lapaʻau a me ka hoʻomohala ʻana i nā mea lapaʻau hou.