Nā huahana

ʻO ka hui 2-[(2R)-2-hydroxy-3-{[4-(3-oxomorpholin-4-yl)phenyl]amino}propyl]-1H-isoindole-1,3(2H)-dione he paʻakikī. mole mole me nā mea hiki ke hoʻohana ʻia ma ke kahua o nā lāʻau lapaʻau a me nā kemika lāʻau.Ua hōʻike ʻia nā derivatives Isoindole e hōʻike i ka nui o nā hana lāʻau lapaʻau, e like me ka anti-inflammatory, antitumor, a me nā waiwai antimicrobial. ʻO ka 2-hydroxy-3-{[4-(3-oxomorpholin-4-yl)phenyl]amino}propyl ʻO ka hui i loko o kēia pūʻulu he pūʻulu hydroxyl (OH) i hoʻopili ʻia i kahi kaulahao kalapona ʻekolu, ʻo ia ka iwi kuamoʻo o kēia moiety.Aia kekahi pūʻulu phenyl i pani ʻia me kahi moiety morpholinone.Ua hoʻohana nui ʻia nā morpholines i ka lāʻau kemika ma muli o ko lākou hiki ke launa pū me nā mea olaola like ʻole a ua hoʻokomo ʻia i loko o nā lāʻau lapaʻau he nui me nā hana like ʻole. hiki iā ʻoe ke hana ma ke ʻano he ligand a i ʻole modulator no nā pahu molekala kikoʻī i loko o ke kino.Ua hoʻohana ʻia nā pūhui carbonyl i ka loaʻa ʻana o ka lāʻau e launa pū me nā enzymes, receptors, a i ʻole nā ​​​​protein e pili ana i nā kaʻina hana maʻi like ʻole. hiki ke hoʻohana.Pono ka noiʻi a me ka hoʻokolohua hou aʻe e hoʻoholo ai i kāna mau waiwai lāʻau lapaʻau. ]-1H-isoindole-1,3(2H)-dione, me kāna isoindole core a me nā hui hana, hiki ke hoʻohana ʻia ma ke kahua o nā lāʻau lapaʻau a me nā kemika lāʻau.Pono e ʻimi hou ʻia kona hoʻohana kikoʻī a me kāna hana ma o ka noiʻi a me ka hoʻokolohua.