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2-(3,5-Dimethyl-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-5,7-dimethoxyquinazolin-4(3H)-one Cas:1044871-04-6 Kiʻi Hōʻikeʻike
  • 2-(3,5-Dimethyl-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-5,7-dimethoxyquinazolin-4(3H)-hoʻokahi Cas:1044871-04-6

2-(3,5-Dimethyl-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-5,7-dimethoxyquinazolin-4(3H)-hoʻokahi Cas:1044871-04-6

ʻO ka wehewehe pōkole:

Ka helu helu: XD90961
Cas: 1044871-04-6
ʻAno Molekala: C24H29N3O4
Kaumaha Molekala: 423.5
Loaʻa: Loaʻa
Kumukuai:  
Hoʻopili mua:  
Pūʻulu Nui: Noi Manao

 


Huahana Huahana

Huahana Huahana

Helu Helu XD90961
inoa mea kūʻai 2-(3,5-Dimethyl-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-5,7-dimethoxyquinazolin-4(3H)-one

CAS

 1044871-04-6

ʻĀpana Molekala

 C24H29N3O4

Kaumaha Molecular

 423.5
Nā kikoʻī mālama  
Kānāwai Kūʻai Kūlike  

 

Huahana Huahana

Ka nana aku  
Hoʻāʻo  
Bwahi ʻaila 612.6±65.0 °C(Wānana ʻia)
ʻO ka mānoanoa 1.25±0.1 g/cm3 (Wānana ʻia)
ʻAkika helu (pKa)9.54±0.20(Wanamua)

 

ʻO RVX-297 kahi mea hoʻopaʻapaʻa BET ikaika loa i koho ʻia no BD2.ʻO nā IC50 o RVX-297 no BRD2(BD2), BRD3(BD2), a me BRD4(BD2) he 0.08, 0.05, a me 0.02 μM.Kāohi ʻo RVX-297 i ka hōʻike ʻana o nā ʻano genes inflammatory cell immune.ʻO ka maikaʻi o RVX-297 i nā hiʻohiʻona preclinical o ka ʻeha a me ka autoimmunity.

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    2-(3,5-Dimethyl-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-5,7-dimethoxyquinazolin-4(3H)-hoʻokahi Cas:1044871-04-6

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