Nā huahana

ʻO ka hui 2-({(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)-1H-isoindole-1, ʻO ka 3(2H)-dione he mole mole kino paʻakikī me nā mea hiki ke hoʻohana ʻia ma nā ʻano lāʻau lapaʻau a me nā lāʻau lapaʻau.Ua hōʻike ʻia nā derivatives Isoindole i nā ʻano lāʻau lapaʻau like ʻole, me ka antitumor, anti-inflammatory, a me nā hana antimicrobial. ʻO ka oxazolidinone moiety, i hōʻike ʻia e ka hui 1,3-oxazolidin-5-yl, ua ʻike ʻia no kāna hana antibacterial.Ua hoʻohana ʻia ʻo Oxazolidinones ma ke ʻano he mea koʻikoʻi i ka lāʻau antibiotic, ʻoi aku ka kūʻē i ka maʻi bacteria kūʻē i ka lāʻau.Hōʻike kēia i hiki ke loaʻa i ka pūhui he mea antibacterial agent. ʻO ka loaʻa ʻana o ka moiety morpholinone, i hōʻike ʻia e ka hui 4- (3-oxomorpholin-4-yl) phenyl, e hoʻohui hou i ka paʻakikī i ka hoʻohana ʻana o ka pūhui.Ua hoʻokomo nui ʻia nā Morpholines i loko o nā pūhui lāʻau lapaʻau ma muli o ko lākou hiki ke launa pū me nā pahuhopu olaola like ʻole.Hiki i ka hui oxo ma ka morpholinone ke hoʻonui i ka pilina o ka pūhui me nā pahuhopu kiko'ī, e lilo ia i mea waiwai nui i ka ʻike a me ka hoʻomohala ʻana i ka lāʻau. ʻO ka 2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]- ʻO ka hui 1,3-oxazolidin-5-yl, i hoʻopili ʻia i ke kumu isoindole, hoʻokumu i ka pae hana nui o ka hui.Hōʻike ka hoʻolālā kemika kikoʻī o kēia pūʻulu e pili ana paha ia me nā pahuhopu biological e like me nā enzymes a i ʻole receptors. ʻO ka holoʻokoʻa, ma muli o nā hiʻohiʻona o ka hui, hiki iā ia ke hōʻike i nā hana pharmacological i nā antibacterial, anti-inflammatory, a me nā wahi therapeutic ʻē aʻe.Eia nō naʻe, pono e hoʻoholo ʻia kāna mau hoʻohana kikoʻī a me nā hana o ka hana ma o nā noiʻi hou aʻe, me nā hoʻokolohua in vitro a in vivo, e loiloi i kona pono a me nā ʻano palekana. -3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)-1H-isoindole-1,3(2H)-dione hōʻike i ka ʻōlelo hoʻohiki ma nā ʻano lāʻau lapaʻau. a me nā lāʻau lapaʻau ma muli o kona ʻano paʻakikī a me nā waiwai lāʻau lapaʻau.Pono ka noiʻi e hiki mai ana e ʻimi i kāna mau hoʻohana kikoʻī, nā noi therapeutic hiki, a me ka pono holoʻokoʻa.