Nā huahana

ʻO 2-Hydroxyphenylboronic acid, i ʻike ʻia hoʻi ʻo ka o-hydroxyphenylboronic acid, he mea hoʻohana nui ʻia i nā ʻano mea like ʻole, me ka synthesis organik, ka ʻepekema waiwai, a me nā kemika lāʻau lapaʻau. he reagent waiwai no ka hoʻokumu ʻana i ka paʻa kalapona kalapona.ʻO nā waikawa Boronic, e like me ka 2-Hydroxyphenylboronic acid, hiki ke hana me nā nucleophiles, e like me nā waiʻona a i ʻole nā ​​amine, e hana i nā esters boronate.Hoʻololi ʻia kēia mau esters boronate, e like me Suzuki-Miyaura cross-coupling reactions, e ʻae ai i ke kūkulu ʻana i nā molekala organik paʻakikī.ʻO kēia ʻano hana like ʻole e hoʻolilo i ka 2-Hydroxyphenylboronic acid i mea kūkulu hale pono i ka synthesis o nā lāʻau lapaʻau, agrochemical, a me nā kemika maikaʻi.No ka laʻana, hiki ke hoʻoneʻe ʻia e hana i nā quinones a i ʻole aryl radical, hiki ke hoʻohana hou ʻia e hoʻohua i nā scaffolds kemika.Hoʻonui kēia mau hoʻololi i ka pono synthetic o ka 2-Hydroxyphenylboronic acid a hiki i ka hana ʻana i nā molekala paʻakikī.ʻO ka pūʻulu hydroxy i loko o ka mole e hiki ai i nā pilina hoʻopaʻa hydrogen ikaika, e lilo ia i hale kūkulu pono no ka hoʻolālā ʻana i nā hui supramolecular a i ʻole nā ​​​​mea hana.ʻO ka hiki ke hana i nā paʻa hydrogen e hiki ai i ka hui pū ʻana o 2-Hydroxyphenylboronic acid i loko o nā nanostructure i wehewehe maikaʻi ʻia a i ʻole ka hoʻololi ʻana o nā ʻili e hāʻawi i nā waiwai i makemake ʻia, e like me ka hydrophilicity i hoʻonui ʻia a i ʻole biocompatibility. ma muli o kona hiki ke ʻano he pūhui bioactive.Hiki i ka boronic acid moiety ke launa pū me nā diols a i ʻole boronate ester-sensitive pūʻulu hana i loko o nā pahuhopu olaola, e lilo ia i mea waiwai i ka hoʻolālā ʻana i nā enzyme inhibitors a i ʻole nā ​​​​ligand receptor.Ua hōʻike ʻia kēia ʻano hana boronate i ka hoʻomohala ʻana i nā lāʻau lapaʻau no nā maʻi like ʻole, e like me ka maʻi kanesa, ka maʻi diabetes, a me ka mumū. ʻO ka holoʻokoʻa, ʻo 2-Hydroxyphenylboronic acid he hui nui me nā noi nui i ka synthesis organik, ʻepekema waiwai, a me nā lāʻau lapaʻau.ʻO kona hoʻoikaika ʻana i ka hoʻokumu ʻana i ka paʻa kalapona-carbon, hiki ke hoʻolauna i nā pūʻulu hana ʻē aʻe, a me ka hiki ke lilo i mea hana bioactive i mea waiwai no ka poʻe noiʻi i nā ʻano ʻepekema like ʻole.