Nā huahana

ʻO 2-Pyrrolidinecarboxamide, 1-(2-chloroacetyl)-, (2S)- he mea hoʻohui i loaʻa nā noi like ʻole ma ke kahua o ka kemika organik a me ka noiʻi lāʻau lapaʻau.ʻO kēia pūhui, i ʻike ʻia ʻo (2S) -2-Pyrrolidinecarboxamido-2-chloroacetic acid amide, e hōʻike ana i nā hiʻohiʻona hiʻona e kūpono ai no kekahi mau hopena kemika a me nā haʻawina biological. hiki ke hoʻohana ʻia ka acid amide ma ke ʻano he mea hoʻomaka a i ʻole waena i ka synthesis o nā molekala paʻakikī.ʻO kona ʻano chiral, me ka inoa (2S), e hōʻike ana he hoʻonohonoho ʻekolu-dimensional kikoʻī o nā mana i hiki ke hoʻololi i ka stereochemistry a me nā waiwai o kāna mau derivatives.He waiwai kēia waiwai i ka hoʻolālā ʻana a me ka hana ʻana i nā lāʻau lapaʻau hou a me nā pūhui lāʻau lapaʻau. nā kaʻina hana ola kino.Ua nānā kekahi mau noiʻi i kāna noi ʻana ma ke ʻano he mea hoʻopale no kekahi mau protease, ʻo ia nā enzyme e pāʻani ana i nā hana physiological like ʻole.Ma ke koho koho ʻana a me ka pale ʻana i kēia mau protease, hiki ke hoʻokō ʻia nā hopena pili i ka therapeutically.Hiki i kēia mau moleke ke hoʻohālike i ke ʻano a me ka hana o nā peptides kūlohelohe, a laila e hoʻohuli ai i nā pahuhopu olaola kūikawā a i ʻole nā ​​​​hana.Hiki i ia mau analogs ke loaʻa nā noi kūpono i ka hoʻomohala ʻana i nā lāʻau lapaʻau no ka mālama ʻana i nā maʻi like ʻole, me ka maʻi kanesa, nā maʻi metabolic, a me nā kūlana neurological. i loko o ka noiʻi hoʻokolohua a ʻaʻole i ʻae ʻia no ka hoʻohana lāʻau lapaʻau.Ke ʻimi ʻia nei nā mea lapaʻau kūpono o ka pūhui, a pono e noiʻi hou ʻia e hoʻoholo i kona palekana a me ka pono i loko o ke kanaka. noiʻi lāʻau lapaʻau.ʻO kona ʻano chiral a me ka hiki ke kāohi i nā enzyme a i ʻole nā ​​​​protein kikoʻī he mea waiwai ia no ka hoʻomohala ʻana i nā lāʻau lapaʻau hou a me nā hoʻolālā therapeutic.ʻOiai ʻo kāna hoʻohana ʻana i ka noiʻi ʻoihana e hōʻike i ka ʻōlelo hoʻohiki, pono ka noiʻi hou ʻana e hoʻomaopopo piha i kona hiki i nā noi lapaʻau.