Nā huahana

ʻO 2,2,2-Trifluoroethanol kahi waiʻona fluorinated e loaʻa ai nā noi nui ma nā ʻano like ʻole, me nā lāʻau lapaʻau, agrochemical, a me nā ʻepekema waiwai.ʻO kāna mau mea kemika kūʻokoʻa e lilo ia i hale kūkulu waiwai a me ka reagent i ka synthesis.One hoʻohana nui o 2,2,2-trifluoroethanol ma ke ʻano he solvent a me ka co-solvent.Loaʻa iā ia ka hiki ke hoʻoheheʻe i kahi ākea o nā pūhui organik a me nā mea ʻole ma muli o kona polarity ikaika a me ka hiki ke hāʻawi i ka paʻa hydrogen.Hoʻohana pono kēia i nā kaʻina hana e pono ai ka hoʻoheheʻe ʻana i nā substrates paʻakikī, e like me nā solutes polar a me nā nonpolar, nā paʻakai metala, a i ʻole nā ​​polymers.Hoʻohana maʻamau ia i ka noiʻi lāʻau lapaʻau a me ka hoʻomohala ʻana ma ke ʻano he mea hoʻoheheʻe no ka peptide synthesis a ma ke ʻano he co-solvent e hoʻonui i ka solubility o nā lāʻau lapaʻau maikaʻi ʻole.Hiki iā ia ke hoʻololi i ka nucleophilic substitution, acylation, a me ka condensation reactions ma muli o ka loaʻa ʻana o kahi pūʻulu trifluoromethyl ikaika electron-withdrawing a me kahi hui hana hydroxy.Hiki ke hoʻoulu ʻia kēia mau hopena ma muli o ka loaʻa ʻana o nā kumu ikaika a i ʻole nā ​​waikawa.He mea waiwai nui ia no nā hopena e koi ai i ka hoʻokomo ʻana a i ʻole ka hoʻololi ʻana o nā trifluoromethyl substituents, no ka mea he kumu ia o ka hui trifluoromethyl.Hiki iā ia ke hana ma ke ʻano he precursor e hana i nā poloka hale trifluoromethylated a i ʻole fluorinated, he mea nui i ka hoʻomohala ʻana i nā lāʻau lapaʻau a me nā agrochemical.Hiki i ka hui trifluoromethyl ke hoʻonui i ka bioactivity a me ka metabolic stability o nā molekala lāʻau, e hoʻolilo iā lākou i mau pahuhopu hoihoi no ka kemika lāʻau lapaʻau. pūhui.Hiki i kēia waiwai ke hoʻokaʻawale i nā enantiomers, ʻo ia nā isomers kiʻi aniani o kahi mole, a he mea koʻikoʻi ia i ka hana ʻana i nā mea lāʻau lapaʻau maʻemaʻe optically. me ka akahele ma muli o kona ʻano mea ʻawaʻawa a hiki i ka pōʻino.ʻO nā hana palekana kūpono, e like me ka hoʻohana ʻana i nā lako pale pilikino a me ka hana ʻana i kahi wahi i hoʻoluʻu maikaʻi ʻia, pono e hahai ʻia e hōʻoia i ka palekana o ka mea hoʻohana a pale aku i ka ʻike ʻole ʻia. e ʻike ai i nā hoʻohana he nui i nā ʻoihana like ʻole.ʻO kona hiki ke hana ma ke ʻano he solvent, reagent, a me chiral resolving agent he mea waiwai ia no nā noi like ʻole, me ka hoʻomohala ʻana i ka lāʻau a me ka synthesis material.Eia nō naʻe, pono e mālama pono i ka wā e hoʻohana ai, e pili ana i nā protocol palekana kūpono e hōʻoia i ka maikaʻi o ka mea hoʻohana a me ka holomua o nā kaʻina hana kemika i makemake ʻia.