Nā huahana

ʻO ka 2,3-Difluoro-4-ethoxybenzeneboronic acid he mea hoʻohui kemika me nā noi koʻikoʻi i ka synthesis organik, ʻoi loa i ka lāʻau lapaʻau a me ka noiʻi lāʻau.He waika boronic derivative e hōʻike ana i kahi apo benzene i pani ʻia me ʻelua mau ʻātoma fluorine, kahi hui ethoxy (-OCH2CH3), a me kahi hui waika boronic (-B(OH)2) ma ke kūlana 4. ʻO kekahi o nā hoʻohana mua o 2, ʻO ka 3-Difluoro-4-ethoxybenzeneboronic acid ka mea i kūkulu ʻia no ka hoʻohui ʻana o nā pūhui hana biologically.ʻO ka hui waika boronic he lima maʻalahi e hiki ke komo i nā ʻano hana kemika, e like me Suzuki-Miyaura cross-coupling reactions, e ʻae ai i ka hoʻokomo ʻana i nā hui hana like ʻole.Hiki ke hoʻohui ʻia kēia pūhui i loko o ka synthesis o nā lāʻau lapaʻau e kuhikuhi ana i nā maʻi kūikawā a me nā kaʻina olaola.Hiki i ka hele ʻana o nā ʻātoma fluorine a me ka hui ethoxy ke hoʻonui i ka metabolic stability, bioactivity, a me nā waiwai pharmacokinetic i nā lāʻau i loaʻa.ʻO ka hui waika boronic kahi pilina kūʻokoʻa no nā diols, i loaʻa maʻamau i nā biomolecules e like me ka saccharides a me nā waikawa nucleic.Hāʻawi kēia waiwai i ka pūhui e hoʻopaʻa paʻa a ʻike i nā molekele i hoʻopaʻa ʻia, hiki ke hoʻolālā i nā mea hana diagnostic koʻikoʻi.ʻO ka hoʻohui ʻana o nā ʻātoma fluorine i loko o ke apo benzene hiki ke hāʻawi i nā waiwai spectroscopic maikaʻi, e like me ka hoʻonui ʻana i ka fluorescence a i ʻole ka hoʻololi ʻana o ka nalu, e hoʻomaikaʻi i ka pololei a me ka hilinaʻi o nā probes. i kona hoʻohana ʻana ma ke ʻano he hale kūkulu hale no ka synthesis o nā mea me nā waiwai holomua.Hoʻohana pinepine ʻia nā derivatives Boronic acid i ka synthesis o nā polymers hana, hiki ke hoʻohana ʻia i nā ʻano ʻano like ʻole, me ka ʻepekema waiwai, nā ʻōnaehana lawe lāʻau, a me nā mea ʻike.ʻO ka hui kūikawā o ka hana boronic acid a me ka fluorine substitution i loko o kēia pūhui e hāʻawi i nā manawa kūpono e hoʻoponopono i nā waiwai o nā mea i loaʻa, e hoʻonui i nā hiʻohiʻona e like me ka solubility, stability, a me ka pilina no nā pahuhopu kiko'ī. , he mea nui e hahai i nā kuʻina palekana kūpono, e like me ke komo ʻana i nā lako pale pilikino a me ka hana ʻana ma kahi wahi i hoʻoluʻu maikaʻi ʻia.Hiki i nā waikona Boronic ke maʻalahi i ka ea a me ka wai, no laila, pono e mālama a mālama iā lākou ma lalo o nā kūlana inert e mālama i ko lākou reactivity a me ke kūpaʻa. ʻo ia hoʻi ma ka lāʻau kemika, ka hoʻomohala ʻana i ka fluorescent probe, a me ka ʻepekema waiwai.ʻO kāna hana waika boronic, me nā pūʻulu fluorine a me ethoxy, hāʻawi i kāna versatility a me nā noi kūpono i ka hoʻolālā ʻana i nā pūhui hana biologically, nā mea hana diagnostic, a me nā mea holomua.ʻO ka hoʻomau ʻana o ka noiʻi ʻana a me ka ʻimi ʻana i kāna hana ʻana a me nā waiwai e hiki ke wehe i nā hoʻohana hou aʻe a hāʻawi i nā ʻike i nā noi hou i nā ʻano ʻepekema like ʻole.