Nā huahana

(2S) -1-(Chloroacetyl) -2-pyrrolidinecarbonitrile he hui ia e paʻa i ka mana nui no nā noi like ʻole i ka noiʻi lāʻau lapaʻau a me ka synthesis organik.ʻO kēia pūhui, i ʻike ʻia ʻo (2S) -2-Chloroacetylpyrrolidine-1-carbonitrile, loaʻa iā ia nā hiʻohiʻona hiʻohiʻona kūʻokoʻa e waiwai ai i ka hoʻomohala ʻana i nā lāʻau lapaʻau hou a me ka hoʻohui ʻana o nā molekala organik paʻakikī. (Chloroacetyl)-2-pyrrolidinecarbonitrile kona hoʻohana ʻana ma ke ʻano he hale kūkulu hale a i ʻole waena i ka synthesis organik.ʻO kāna hui chloroacetyl reactive a me ka hui cyano (carbonitrile) e ʻae i ka hoʻokomo ʻana i nā pūʻulu hana hou a me ka hoʻokumu ʻana i nā mea paʻa kemika hou.Hoʻohana kēia versatility i mea pono i ka synthesis o nā pūhui like ʻole, me nā lāʻau lapaʻau, agrochemicals, a me nā kemika kūikawā. kumu i ka hoʻolālā lāʻau.Hiki ke hoʻopili ʻia ka hoʻolālā kūʻokoʻa a me nā pūʻulu hana me nā pahuhopu olaola kikoʻī, e like me nā enzymes, receptors, a i ʻole nā ​​protein, a laila e hoʻololi i kā lākou hana.Ma ka hoʻololi ʻana i nā ʻāpana like ʻole o ka mole, hiki i nā mea noiʻi ke aʻo a hoʻopaʻa i kāna mau waiwai pharmacological, hiki ke alakaʻi i ka hoʻomohala ʻana i nā mea lapaʻau hou. noiʻi.Hiki ke hoʻohana ʻia e lepili i nā protein target a i ʻole nā ​​molekole hoihoi, e hāʻawi ana i kahi ala e aʻo ai i kā lākou ʻano a me ka launa pū ʻana i loko o nā ʻōnaehana biological.Ma ka hoʻopili ʻana i nā hōʻailona kūpono a i ʻole nā ​​lepili i kēia pūhui, hiki i nā mea noiʻi ke hahai i kona puʻunaue ʻana a me nā ʻano hoʻopaʻa paʻa, e kōkua ana i ka ʻike maikaʻi ʻana i nā kaʻina olaola. 2S), wehe i nā mea hiki ke hoʻohana i ka synthesis asymmetric.Loaʻa i nā pūhui Chiral nā hoʻonohonoho like ʻole o nā ʻātoma i loko o ko lākou ʻano, e hāʻawi ana i ka hiki ke hana i nā pūhui enantiopure, ʻo ia nā molekole e noho nei i loko o hoʻokahi wale nō o nā ʻano kiʻi aniani ʻelua.He waiwai nui kēia waiwai i ka loaʻa ʻana o ka lāʻau lapaʻau, no ka mea, hiki i nā lāʻau enantiopure ke hōʻike i ka hana pharmacological i hoʻonui ʻia a hoʻemi ʻia nā hopena ʻaoʻao. hoʻohuihui.Loaʻa iā ia ka mea hiki ke lawelawe ma ke ʻano he hale kūkulu no ka synthesis o nā molekala organik paʻakikī, ma ke ʻano he wahi hoʻomaka no ka hoʻomohala ʻana i ka lāʻau lapaʻau, a ma ke ʻano he mea hana no ka noiʻi biochemical a me ke olaola.ʻO ka ʻimi hou ʻana a me ka noiʻi ʻana i kāna mau waiwai e hoʻonui i ko mākou ʻike i kāna mau noi kūpono a hiki ke alakaʻi i ka loaʻa ʻana o nā mea lapaʻau hou.