Nā huahana

ʻO 3-Fluoro-4'-propyl-biphenylboronic acid he mea hoʻohui kemika e pili ana i ka papa o nā waikawa boronic.Loaʻa iā ia kahi apo biphenyl me kahi pūʻulu propyl i hoʻopili ʻia i kekahi ʻaoʻao a me kahi atom fluorine i hoʻopili ʻia i kekahi ʻaoʻao, a me kahi hui waikawa boronic.He nui nā noi o kēia pūhui ma nā kahua o ka synthesis organik, kemika lāʻau lapaʻau, a me ka ʻepekema waiwai. ʻO kekahi o ka hoʻohana mua ʻana o 3-Fluoro-4'-propyl-biphenylboronic acid he mea hoʻohui i ka hui ʻana i ka synthesis organik.Hoʻohana maʻamau ia ma Suzuki-Miyaura cross-coupling reactions, ʻo ia nā ala ikaika no ka hana ʻana i nā paʻa kalapona kalapona.Hana ʻia kēia pūhui ma ke ʻano he ester boronate, e hana ana me ka aryl a i ʻole vinyl halides ma lalo o ka palladium catalysis e hana i nā pūhui biaryl a i ʻole styryl.Hiki i ka hele ʻana o ka fluorine atom a me ka hui propyl i loko o ka hale ke hoʻololi i ka reactivity a me ke koho ʻana o ka hopena cross-coupling, e hoʻolilo iā ia i mea kūkulu hale versatile no ka synthesis o nā molekala organik paʻakikī. -4'-propyl-biphenylboronic acid hiki ke hoʻohana ʻia no ka hoʻolālā ʻana a me ka synthesis o nā pūhui hana biologically.ʻO ka hiki ʻana o ka hui waikawa boronic e hiki ai ke hoʻokumu i nā paʻa covalent reversible me nā biomolecules, e like me nā enzymes a i ʻole nā ​​​​protein receptor.ʻIke ʻia kēia mau pūhui he mau mea hoʻopaneʻe boronate a hiki ke hoʻohana ʻia no ka huli ʻana i nā enzyme kikoʻī i pili i nā maʻi e like me ke kanesa a i ʻole ka maʻi diabetes.Hiki i ka fluorine atom a me ka hui propyl ke kōkua i ka hoʻonui ʻana i nā waiwai pharmacological o kēia mau pūhui, e like me ka potency, selectivity, a me ka metabolic stability.ʻIke ʻia nā waikawa Boronic no ko lākou hiki ke hana me nā diols a i ʻole polyols, e hana ana i nā paʻa covalent ikaika.Hiki ke hoʻohana ʻia kēia waiwai i ka ʻepekema polymer e hana i nā mea hoʻōla ponoʻī a i ʻole nā ​​hui supramolecular.Ma ka hoʻokomo ʻana i kēia pūhui i loko o nā polymers a i ʻole nā ​​uhi, hiki i nā mea noiʻi ke hoʻolauna i ka hana boronic acid, e ʻae ana i nā loulou reversible a me ka hiki ke hoʻoponopono i ka pōʻino a hoʻihoʻi paha i nā waiwai mechanical. me nā noi i ka synthesis organik, kemika lāʻau lapaʻau, a me ka ʻepekema waiwai.Hāʻawi kona reactivity a me nā hui hana kūikawā i nā manawa no ka hoʻokumu ʻana i nā paʻa kalapona-carbon i nā hopena cross-coupling, ka hoʻolālā ʻana a me ka synthesis o nā pūhui hana biologically, a me ka hana ʻana i nā mea ikaika.Hoʻonui ka pūʻulu fluorine a me propyl i ka hoʻoulu ʻana o ka pūhui a hoʻoikaika i kona mau waiwai lāʻau lapaʻau a mea waiwai paha.Hoʻohana kēia mau hiʻohiʻona i ka 3-Fluoro-4'-propyl-biphenylboronic acid i mea waiwai no nā ʻepekema a me nā mea noiʻi ma nā ʻoihana like ʻole, e hāʻawi ana i nā holomua i ka ʻike ʻana i ka lāʻau lapaʻau, ka ʻenekinia waiwai, a me nā ʻoihana e pili ana.