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ʻO 3-Methyl-7-(2-butyn-1-yl) -8-bromoxanthine he mea hoʻohui kemika no ka ʻohana xanthine.Ua aʻo nui ʻia nā derivatives Xanthine a ua ʻike ʻia no kā lākou ʻano like ʻole o nā noi, ʻo ia hoʻi ma ke kahua o ka pharmacology. ma ke ʻano he lāʻau lapaʻau no ka mālama ʻana i nā maʻi hanu e like me ka hānō a me ka maʻi obstructive pulmonary maʻi (COPD).ʻO Xanthine derivatives, me ka theophylline, ua hoʻohana lōʻihi ʻia i ka lāʻau hanu ma muli o kā lākou bronchodilator a me nā mea anti-inflammatory.Ke hana nei kēia mau pūhui ma ka hoʻomahaʻana i nāʻiʻo maʻemaʻe ma nā alaloa a me ka ho'ēmiʻana i ka mumū, pēlā e hoʻonui ai i ka hana hanu. Hiki i ka -8-bromoxanthine ke hoʻonui i kona mau hopena bronchodilatory i hoʻohālikelike ʻia me nā derivatives xanthine ʻē aʻe.Ua hōʻike ʻia ka hoʻololi ʻana o Bromine i nā pūhui like e hoʻonui i ko lākou ikaika a me ka lōʻihi o ka hana.No laila, hiki i kēia pūhui ke lilo i bronchodilator ʻoi aku ka maikaʻi a me ka lōʻihi no nā maʻi hanu.Ua hōʻike lākou i nā hopena antioxidant a me nā anti-inflammatory, a me ka hiki ke hoʻoikaika i ke kahe koko cerebral a hoʻomaikaʻi i ka hana cognitive.Hoʻolilo kēia mau waiwai iā lākou i mau moho hoihoi no nā maʻi neurodegenerative e like me nā maʻi o Alzheimer a me Parkinson.Hoʻohana pinepine ʻia nā derivatives Xanthine e like me nā mea hana biochemical e aʻo ai i nā adenosine receptors a me nā enzyme phosphodiesterase.Hiki i kēia mau pūhui ke hana ma ke ʻano he ligand koho a i ʻole nā ​​mea hoʻopaneʻe, e kōkua ana i ka noiʻi ʻana i nā mīkini molekala kūikawā a me nā ala. hoʻonui i kāna mau waiwai no nā noi kikoʻī.Hiki ke hoʻohana ʻia nā ʻano hana kemika like ʻole, e like me ka hoʻololi ʻana, ka hoʻohui ʻana, a me ka hoʻohui ʻana, e hoʻolauna i nā pūʻulu hana a i ʻole e hoʻololi i ke ʻano kumu.Hiki i kēia mau hoʻololi ke hoʻonui i kāna mau hana pharmacological a i ʻole hiki ke hoʻomohala i nā derivatives me ka hoʻomaikaʻi ʻana i ka koho a me ka bioavailability. , neuroprotection, a me ka noiʻi biochemical.ʻO kāna mau hopena bronchodilator e lilo ia i moho hoʻohiki no ka mālama ʻana i nā maʻi hanu, a ʻo kāna mau waiwai neuroprotective hiki ke hōʻike i nā noi i nā maʻi neurodegenerative.Pono ka noiʻi a me ka hoʻomohala hou ʻana e ʻimi a hoʻohana pono i nā pono o kēia pūhui ma nā ʻano lāʻau lapaʻau a ʻepekema.