Nā huahana

ʻO ka 4-Carboxyphenylboronic acid kahi mea hoʻohui i ka ʻohana o nā waikawa boronic.ʻO kona ʻano kemika he ʻātoma boron i hoʻopili ʻia i kahi hui carboxyphenyl.Ua loaʻa i kēia pūhui nā noi he nui ma nā ʻano like ʻole e like me ka synthesis organik, ʻepekema waiwai, kemika lāʻau lapaʻau, a me ka catalysis.Hoʻohana maʻamau ia ma ke ʻano he reagent i ka palladium-catalyzed cross-coupling reactions, kikoʻī ma Suzuki-Miyaura a me Chan-Lam hui pū ʻana.Ma ke komo ʻana ma ke ʻano he kumu boron, hiki iā ia ke hana i nā paʻa kalapona-carbon me nā substrates organik, e like me ka aryl a i ʻole vinyl halides.ʻAe kēia i ka poʻe chemist e hana i nā molekala organik paʻakikī a me nā pūhui hana pono.ʻO ka hiki ke hoʻolauna i ka hui carboxyphenyl e hāʻawi i ka versatility i ka hoʻololi ʻana a me ka hoʻopili ʻana i nā waiwai o nā pūhui hopena.Hāʻawi ia i ka hoʻokomo ʻana i ka moiety acid boronic, ka mea e hāʻawi i nā hiʻohiʻona kūʻokoʻa a me ka reactivity i nā pūhui i manaʻo ʻia.No ka laʻana, hiki i nā waikawa boronic ke hana ma ke ʻano he protease inhibitors, a ma ka hoʻopili ʻana i ka hui carboxyphenylboronic acid, hiki i nā mea noiʻi ke hoʻololi i ka hana enzyme a i ʻole ke hoʻolālā ʻana i nā mea hoʻopanee i hoʻopaʻa ʻia i ka enzyme.Eia kekahi, ʻo ka loaʻa ʻana o ka hui carboxylic acid e hiki ai i ka hui ke hana i nā paʻa hydrogen me nā biomolecules, e hoʻonui ai i kona pili ʻana i nā mea hoʻokipa protein, no laila e hoʻohuli ai i kā lākou hana ola. nā mea paʻa me nā polyols a i ʻole nā ​​pūhui hydroxyl.Hāʻawi kēia waiwai iā ia e hoʻohana ma ke ʻano he ʻāpana i ka synthesis o nā mea holomua e like me nā hydrogels, bioconjugates, a i ʻole nā ​​polymers stimuli-responsive.Ma ka hoʻokomo ʻana i ka 4-Carboxyphenylboronic acid i loko o kēia mau mea, hiki ke hoʻopili ʻia ko lākou mau waiwai, e ʻae i nā noi e like me nā ʻōnaehana lawe lāʻau, nā mea ʻike, a me nā mea akamai. .Hiki iā ia ke komo i ka acid-base catalysis, esterification, a me nā hopena amidation.Hiki ke hoʻohana ʻia kēia hana catalytic i ka synthesis o nā lāʻau lapaʻau, nā kemika maikaʻi, a me nā molekala ʻē aʻe.Loaʻa kāna mau noi mai ka synthesis organik a me ke kemika lāʻau lapaʻau i ka ʻepekema waiwai a me ka catalysis.ʻO kona hiki ke komo i loko o ka palladium-catalyzed cross-coupling reactions, kona hiki ke lilo i poloka hale no nā pūhui hana biologically, a me kāna hana ma ke ʻano he mea hoʻoikaika i mea pono no ka poʻe noiʻi i ka ʻimi ʻana i ka holomua ʻike a me ka hoʻomohala ʻana i nā hopena hou.