Nā huahana

5-(Bromomethyl) -4-(4-fluorophenyl) -6-isopropyl-2- [methyl(methylsulfonyl) amino] pyrimidine he mea hoʻohui kemika e loaʻa ana ka pono ma nā noiʻi like ʻole, lāʻau lapaʻau, a me nā noi ʻoihana.ʻIke ʻia kēia pūhui no kona ʻano maʻalahi a me ka hiki ke paʻa no ka hoʻomohala ʻana i nā molekele kūʻokoʻa a me nā lāʻau lapaʻau ma muli o kāna ʻano kikoʻī a me nā pūʻulu reactive. lāʻau lapaʻau.ʻO ka loaʻa ʻana o kahi bromine atom, fluorine atom, isopropyl group, a me ka pyrimidine ring structure e lilo ia i mea hale nani no ka hana ʻana i nā molekala hou me nā waiwai i makemake ʻia.Hiki i nā kemika a me nā mea noiʻi lāʻau lapaʻau ke hoʻololi a hana i kēia pūhui e hoʻolauna i nā hana kikoʻī a i ʻole nā ​​hiʻohiʻona hoʻolālā e pono ai no ka hana lāʻau lapaʻau i manaʻo ʻia a i ʻole nā ​​waiwai pharmacokinetic i hoʻonui ʻia.Hiki i ka hui methylsulfonyl ke hana i nā ʻano like ʻole, e like me ka nucleophilic displacement, elimination, a i ʻole oxidation, e ʻae ai i ka hoʻokomo ʻana i nā pūʻulu hana like ʻole i loko o ka moleke.He mea waiwai kēia no ka hana ʻana i nā pūhui organik paʻakikī i ka hoʻonohonoho hoʻokolohua.Hiki ke kōkua ka fluorine atom a me kekahi mau mea pani i nā waiwai kino a i ʻole kemika o ka pūhui, i mea maikaʻi no ka noiʻi ʻana i kekahi mau hanana a i ʻole ma ke ʻano he hui kuhikuhi no nā haʻawina hoʻohālikelike.Hoʻohana pinepine ka poʻe noiʻi i ia mau pūhui no ka hoʻomaopopo ʻana i ka pilina olaola, ke aʻo ʻana i nā kinetics reaction, hoʻomohala i nā ʻano hana synthetic hou, a i ʻole e hoʻomaikaʻi i ka hana o nā kaʻina hana ʻenehana. 4-fluorophenyl) -6-isopropyl-2- [methyl(methylsulfonyl) amino] pyrimidine hiki ke hoʻololi ma muli o ka wahi kikoʻī o ka noiʻi a i ʻole ka ʻoihana.ʻO ka hoʻohana pono ʻana o ka pūhui e ʻoi aku ma mua o nā mea i ʻōlelo ʻia ma mua, a hiki ke ʻimi ʻia kona pono e nā chemists, pharmacologists, biochemists, a me nā kānaka ʻepekema ʻē aʻe e pili ana i ka ʻimi lāʻau, ʻepekema waiwai, a i ʻole noiʻi molekala. -(4-fluorophenyl) -6-isopropyl-2- [methyl(methylsulfonyl) amino] pyrimidine he mea hoʻohui like ʻole e paʻa ana i ka ʻōlelo hoʻohiki i ka noiʻi lāʻau lapaʻau, kemika, a me ka ʻenehana.ʻO kona ʻano kikoʻī a me nā pūʻulu reactive e lilo ia i poloka hale nani no ka hoʻohui ʻana i nā molekala lāʻau hou a me ka noiʻi ʻana i nā hopena kemika.He ākea ka hoʻohana ʻana o ka pūhui, a ʻo ka ʻimi hou ʻana i kāna mau waiwai e hoʻolalelale i ke ala no ka holomua ma nā ʻano ʻepekema.