Nā huahana

ʻO 5,6,7,7a-Tetrahydrothieno[3,2-c]pyridine-2(4H)-one hydrochloride, i kapa ʻia ʻo riluzole hydrochloride, he lāʻau lapaʻau i hoʻohana mua ʻia i ka mālama ʻana i ka amyotrophic lateral sclerosis (ALS), ʻike pū ʻia ʻo Lou Gehrig's disease.He lāʻau lapaʻau waha e hana ana ma ka hoʻololi ʻana i nā pae o ka glutamate, kahi neurotransmitter excitatory, i loko o ka lolo. Manaʻo ʻia ʻo Riluzole hydrochloride e hana ma ka hoʻemi ʻana i ka hoʻokuʻu ʻana i ka glutamate, ke kāohi ʻana i ka glutamate uptake, a me ka pale ʻana i nā mea loaʻa glutamate.Manaʻo ʻia ʻo Glutamate ka hana i ka holomua o ka ALS a ma ka hoʻololi ʻana i kona mau pae, hiki i ka riluzole hydrochloride ke hoʻolohi i ka degeneration o nā neurons motor a hiki ke kōkua i ka hoʻolōʻihi ʻana i ke ola. hiki ke hoʻohana ʻia i nā maʻi neurological ʻē aʻe e like me ka maʻi o Alzheimer, ka sclerosis lehulehu, a me ke kaumaha.Eia naʻe, ke aʻo ʻia nei kona pono i kēia mau kūlana a koi hou ʻia ka noiʻi. E like me nā lāʻau lapaʻau, hiki i ka riluzole hydrochloride ke hana i nā hopena ʻaoʻao.ʻO nā hopena ʻaoʻao maʻamau e pili ana i ka nausea, ka luaʻi ʻana, ka noʻonoʻo, nāwaliwali, a me ka ʻeha o ka ʻōpū.Hiki i nā hopena ʻaoʻao maʻamau akā ʻoi aku ke koʻikoʻi ke komo i nā pilikia o ka ate, nā hopena maʻi, a me nā loli i ka helu koko.He mea nui e kūkākūkā i nā pilikia a me nā pōmaikaʻi me ka ʻoihana mālama ola ma mua o ka hoʻomaka ʻana i ka riluzole hydrochloride. I ka hopena, 5,6,7,7a-Tetrahydrothieno[3,2-c]pyridine-2(4H)-one hydrochloride, a i ʻole riluzole hydrochloride, he lāʻau lapaʻau i hoʻohana ʻia e mālama i ka ALS ma ka hoʻololi ʻana i nā pae glutamate i loko o ka lolo.ʻOiai he mea maikaʻi ia i ka hoʻolohi ʻana i ka piʻi ʻana o ka ALS, hiki nō ke kumu i nā hopena ʻaoʻao e pono ke nānā ʻia.Ke noiʻi ʻia nei kona hoʻohana ʻana i nā kūlana neurological ʻē aʻe.