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BCIP-Toluidine)5-Bromo-4-chloro-3-indolylphosphate-p-toluidine salt Cas:6578-06-9 99% Keʻokeʻo i ka pauka ʻeleʻele ʻulaʻula Kiʻi ʻia
  • BCIP-Toluidine)5-Bromo-4-chloro-3-indolylphosphate-p-toluidine salt Cas:6578-06-9 99% Keʻokeʻo i ka pauka ʻeleʻele māmā

BCIP-Toluidine)5-Bromo-4-chloro-3-indolylphosphate-p-toluidine salt Cas:6578-06-9 99% Keʻokeʻo i ka pauka ʻeleʻele māmā

ʻO ka wehewehe pōkole:

Ka helu helu: XD90137
Cas: 6578-06-9
ʻAno Molekala: C8H5BrClNO4P·C7H10N
Kaumaha Molekala: 433.62
Loaʻa: Loaʻa
Kumukuai:  
Hoʻopili mua: 5g USD20
Pūʻulu Nui: Noi Manao

 

 

 

 

 

 

 


Huahana Huahana

Huahana Huahana

Helu Helu XD90137
inoa mea kūʻai BCIP-Toluidine)5-Bromo-4-chloro-3-indolylphosphate-p-toluidine paʻakai
CAS 6578-06-9
ʻĀpana Molekala C8H5BrClNO4P·C7H10N
Kaumaha Molecular 433.62
Nā kikoʻī mālama -15 a -20 °C
Kānāwai Kūʻai Kūlike 29339980

 

Huahana Huahana

Ka nana aku ʻO ka pauka keʻokeʻo/ʻeleʻele māmā
ʻO Assay ≥ 99%
Lae hehee 194-195 ºC
Lae paila 580.2°C ma 760 mmHg
Kuhikuhi uila 304.7°C
Ka hikiwawe DMF: 20 mg/mL
Ka hikiwawe hiki ke hoʻoheheʻe ʻia i ka dimethylformamide, hiki ʻole ke hoʻoheheʻe ʻia i ka wai.
ʻO ka naʻau Paʻa i ka māmā, ʻoluʻolu i ka ea, a pili i ka wela

 

Hana olaola: BCIP (BCIP p-toluidine paʻakai; X-phosphate p-toluidine paʻakai) he substrate chromogenic no ka ʻike colorimetric o ka hana alkaline phosphatase.

Hoʻopuka ʻia nā toxins Shiga (Stxs) e enterohemorrhagic Escherichia coli (EHEC), ka mea e hoʻoulu ai i nā maʻi kanaka me kahi hopena make.ʻO nā laina kelepona ʻo Vero, i loaʻa mai ʻApelika ʻōmaʻomaʻo monkey kidney, e hōʻike ana i ke kūlana gula no ka hoʻoholo ʻana i nā hopena cytotoxic o Stxs.ʻOiai ʻo kā lākou hoʻohana honua, ʻaʻole maikaʻi ka ʻike e pili ana i nā kūkulu kikoʻī o ka Stx receptor glycosphingolipids (GSLs) a me kā lākou hui ʻana i nā raft lipid.Maʻaneʻi mākou e hōʻike nei i kahi loiloi hoʻolālā piha o Stx receptor GSLs a me kā lākou hāʻawi ʻana i nā membranes detergent-resistant (DRMs), i hoʻomākaukau ʻia mai nā cell Vero-B4 a hoʻohana ʻia e like me ka lipid raft equivalents.Ua ʻike mākou i ka globotriaosylceramide (Gb3Cer) a me ka globotetraosylceramide (Gb4Cer) e like me nā mea hoʻokipa GSL no Stx1a, Stx2a, a me Stx2e subtypes e hoʻohana ana i ka ʻike overlay TLC i hui pū ʻia me MS.ʻO ka mea loaʻa Stx maʻamau, globopentaosylceramide (Gb5Cer, Galβ3GalNAcβ3Galα4Galβ4Glcβ1Cer), i ʻike pono ʻia (ma kahi o Gb3Cer a me Gb4Cer) e Stx2e, ua hoʻohālikelike piha ʻia.Ua ʻike ʻia nā lipoforms o Stx receptor GSLs i ka nui o nā ceramide moieties i haku ʻia me sphingosine (d18:1) a me C24:0/C24:1 a i ʻole C16:0 fatty acid.Eia kekahi, ʻo ka hui pū ʻana me nā māka lāʻau lipid, SM a me ka cholesterol, i ka DRMs i manaʻo i ka hui GSL me nā microdomains membrane.Hāʻawi kēia haʻawina i ke kumu no ka ʻimi hou ʻana i ka hopena hana o nā lipid raft-like Stx receptors no ka hōʻeha ʻana i ka toxin-mediated o nā cell Vero-B4.

 

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    BCIP-Toluidine)5-Bromo-4-chloro-3-indolylphosphate-p-toluidine salt Cas:6578-06-9 99% Keʻokeʻo i ka pauka ʻeleʻele māmā

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