D-Glutamic acid CAS: 6893-26-1 99% ʻO ka pauka keʻokeʻo
| Helu Helu | XD90313 |
| inoa mea kūʻai | D-Glutamic acid |
| CAS | 6893-26-1 |
| ʻĀpana Molekala | C5H9NO4 |
| Kaumaha Molecular | 147.13 |
| Nā kikoʻī mālama | Ambient |
| Kānāwai Kūʻai Kūlike | 29224200 |
Huahana Huahana
| Ka nana aku | ʻO ka pauka kristal keʻokeʻo |
| Hoʻāʻo | 99% |
| Kahuli kiko'ī | -31 a i -32.2 |
| Nā metala kaumaha | <10ppm |
| AS | <1ppm |
| pH | 3 - 3.5 |
| SO4 | <0.020% |
| Fe | <10ppm |
| Nalo ma ka maloo | <0.20% |
| Koena ma ka Ignition | <0.10% |
| NH4 | <0.02% |
| Cl | <0.02% |
| Mokuaina o ka hooponopono | >98% |
Hoʻokaʻawale ʻo γ-Glutamyltranspeptidases (γ-GTs) i ka paʻa γ-glutamyl amide o ka glutathione a hoʻololi i ka hui γ-glutamyl i hoʻokuʻu ʻia i ka wai (hydrolysis) a i ʻole nā ʻakika amino acceptor (transpeptidation).ʻO kēia mau enzymes ubiquitous ke kuleana nui i ka biosynthesis a me ka degradation o glutathione, a me ka detoxification xenobiotic.Maʻaneʻi mākou e hōʻike nei i ka 3Å hoʻonā aniani hoʻonā o Bacillus licheniformis γ-GT (BlGT) a me kona paʻakikī me l-Glu.Hōʻoia nā hale X-ray e pili ana ʻo BlGT i ka N-terminal nucleophilic hydrolase superfamily a hōʻike ʻia aia ka pūmua i ka wehe ʻana o ka wahi hana e like me ka mea i hōʻike ʻia no ka enzyme homologous mai Bacillus subtilis, akā ʻokoʻa i nā mea i ʻike ʻia no ke kanaka γ-GT a no nā γ-GT mai nā microorganism ʻē aʻe.Hōʻike ka ʻikepili i ka hoʻopaʻa ʻana o ka l-Glu i ka hoʻonohonoho hou ʻana o ka huelo C-terminal o BlGT subunit nui a ʻae i ka ʻike ʻana i kahi pūʻulu o nā koena waikawa i komo i ka ʻike ʻana i kahi ion metala.Ua aʻo ʻia ke kuleana o kēia mau koena ma ka conformational stability o BlGT ma ke ʻano o ka autoprocessing, hana enzymatic, kemika a me ka thermal denaturation o ʻehā mau mutants Ala hou.Hōʻike nā hopena i ka hoʻololi ʻana o Asp568 me kahi Ala e pili ana i ka autoprocessing a me ka paʻa o ka protein.
