Nā huahana

ʻO ka mea nui n-3 fatty acid α-linolenic acid (C18: 3) lawelawe ma ke ʻano he mea lawe ikehu a me ka precursor no ka synthesis o EPA (C20: 5) a me DHA (C22: 6) kahi i hoʻololi ʻia e ka elongation kaulahao a me ka hoʻokomo. o na paa palua keu.He mea nui ka EPA o ka phospholipids o nā membrane cell a me nā lipoproteins.Hoʻohana ia ma ke ʻano he precursor i ka synthesis o eicosanoids, nona ka hana hoʻoponopono i nā hormones kiko.ʻO DHA kahi mea i kūkulu ʻia i loko o nā membrane cell, ʻo ia hoʻi ka ʻiʻo nerve o ka lolo, a he hana koʻikoʻi ia no nā synapses a me nā cell o ka retina.

ʻAʻole lawa paha ka hoʻololi ʻana o ka α-linolenic acid i kāna mau kaulahao lōʻihi EPA a me DHA no ka mālama ʻana i nā hana maikaʻi o ke kino.ʻO ka hoʻololi liʻiliʻi ma muli o ka loli nui o ka ʻai ʻana i nā makahiki 150 i hala iho nei, ka hopena o ka hoʻonui ʻana i ka n-6 PUFA intake a me ka hoʻemi like ʻana o ka hoʻohana ʻana i ka n-3 LCPUFA i ka hapa nui o nā ʻāina ʻoihana.No laila, ua loli ka lakio n-6 a i ka n-3 i kā mākou meaʻai mai ka 2:1 a hiki i ka 10 - 20:1.Hoʻololi kēia hoʻololi i ka biosynthesis kūpono ʻole o ka n-3 PUFA, EPA, a me DHA biologically active, ʻoiai ʻo n-6 a me n-3 PUFA e hoʻokūkū nei no ka desaturase a me nā ʻōnaehana enzyme elongase.