Erythromycin CAS:114-07-8 99% Keokeo crystalline pauda
| Helu Helu | XD90353 |
| inoa mea kūʻai | Erythromycin |
| CAS | 114-07-8 |
| ʻĀpana Molekala | C37H67NO13 |
| Kaumaha Molecular | 733.93 |
| Nā kikoʻī mālama | Ambient |
| Kānāwai Kūʻai Kūlike | 29415000 |
Huahana Huahana
| ʻIkepili | IR absorption spectrum hoohalike me USP RS |
| Wai | 10% ka nui |
| Ethanol | 0.5% ka nui |
| Koena ma ka Ignition | 0.2% ka nui |
| Hoʻāʻo | 99% |
| Kahuli kiko'ī | -71 ° a i -78 ° |
| Ka nana aku | ʻO ka pauka kristal keʻokeʻo |
| Crystallinity | Kū i nā koi |
| Erythromycin B | 12.0% ka nui |
| ErythromycinC | 5.0% ka nui |
| Ka palena o ka thiocyanate | 0.3% ka nui |
| Propanol | 0.5% ka nui |
| N-butyl acetate | 0.5% ka nui |
| Erythromycin He enol ether | 0.3% ka nui |
| Kekahi mea pili kanaka | 3.0% ka nui |
Ma ka haʻawina o kēia manawa, ua nānā mākou i ka launa pū ʻana o nā mea antimicrobial me ʻehā mau hiʻohiʻona lipid membrane e hoʻohālike i nā membrane cell mammalian a me nā membrane bacterial Gram-positive a -negative a nānā i nā kinetics paʻa me ka hoʻohana ʻana i kā mākou ʻenehana plasmon resonance (SPR).Ua koho ʻia nā hiʻohiʻona paʻa koho a me nā kikoʻī o nā mea antimicrobial i nā membrane lipid, a ua loiloi ʻia nā ʻāpana kinetic ma o ka hoʻohana ʻana i kahi ʻano hoʻohālike ʻelua mokuʻāina.Ua ʻike ʻia ka loiloi reproducible o nā kinetics paʻa.ʻO Vancomyicn, teicoplanin, erythromycin, a me linezolid i hōʻike liʻiliʻi i ka launa pū ʻana me nā membrane lipid ʻehā i ka ʻōnaehana SPR.Ma ka ʻaoʻao ʻē aʻe, hōʻike nā analogues vancomycin i ka launa pū ʻana me nā membrane lipid model i ka ʻōnaehana SPR.Kūkākūkā ʻia nā hiʻohiʻona koho a me nā kikoʻī paʻa o nā analogues vancomycin i nā membrane lipid ma muli o ka ʻikepili no nā hana antibacterial in vitro a me kā mākou ʻikepili e pili ana i ka pilina paʻa o ka D-alanyl-D-ala ʻeiwa ʻeiwa o kahi pā cell pentapeptide i loaʻa e SPR.Hiki ke loiloi ʻia ke ʻano o ka hana antibacterial e kūʻē iā Staphylococcus aureus a me vancomycin-resistant enterococci me ka hoʻohana ʻana i ka pilina paʻa i loaʻa me kā mākou ʻenehana SPR.Hōʻike nā hopena i hiki ke hoʻohana nui ʻia ke ʻano SPR e wānana i nā ʻano paʻa, e like me ke koho a me ka kikoʻī, o nā mea antimicrobial he nui i nā membrane lipid.
