ʻOmaomao māmā SF Cas: 5141-20-8 Poni poni hohonu
| Helu Helu | XD90538 |
| inoa mea kūʻai | SF ʻōmaʻomaʻo māmā |
| CAS | 5141-20-8 |
| ʻĀpana Molekala | C₃₇H₃₄N₂Na₂O₉S₃ |
| Kaumaha Molecular | 792.86 |
| Nā kikoʻī mālama | -15 a -20 °C |
| Kānāwai Kūʻai Kūlike | 32129000 |
Huahana Huahana
| Ka nana aku | Pauka poni hohonu |
| Hoʻāʻo | 99% |
| Ka hikiwawe | Hiki ke hoʻoheheʻe ʻia i ka wai e hāʻawi i kahi ʻōmaʻomaʻo ʻōmaʻomaʻo |
No ka loiloi systematically i nā hiʻohiʻona staining a me ka palekana o nā mea hou e hiki ai ke ʻoki intraocular. Ua hoʻokomo ʻia nā ʻeono i loko o ka hoʻokolokolo: ʻōmaʻomaʻo māmā SF (LGSF) melemele, E68, bromophenol blue (BPB), Chicago blue (CB), rhodamine 6G, rhodulinblau -kumu 3 (RDB-B3).Ua hoʻoheheʻe ʻia nā mea pena a pau i loko o kahi wai paʻakai paʻakai.Ua ana ʻia nā waiwai hoʻomaʻamaʻa kukui o kēlā me kēia kala ma kahi ʻano o 0.05% ma waena o 200 a me 1000 nm.Ua nānā ʻia nā hiʻohiʻona staining e ka staining lens capsule tissue a me nā epiretinal membranes (ERMs), wehe ʻia i loko o ka hana, me ka nui o ka wai o 1.0%, 0.5%, 0.2%, a me 0.05%.ʻO nā maka puaʻa enucleated (ka manawa postmortem, 9 mau hola) ua ʻino pū ʻia.Ua loiloi ʻia nā mea ʻawaʻawa e pili ana i ka wai e ka hoʻāʻo colorimetric (MTT) e ana ana i ka pale ʻana i ka hoʻonui ʻana o ka retinal pigment epithelium (RPE) cell proliferation (ARPE-19 a me nā cell RPE kanaka mua, nā paukū 3-6).Ua helu pū ʻia ka hiki ʻana o ke kelepona ma muli o ka ʻike ʻana i ka hoʻāʻo ʻana o ka cell-viability cell fluorescence ʻelua.Ua noiʻi ʻia nā dyes ma nā ʻano o 0.2% a me 0.02%. ʻO nā dyes a pau i noiʻi ʻia i loko o kēia haʻawina i hoʻopaʻa ʻia i nā capsule lens kanaka, wehe ʻia intraoperatively;ʻO nā ERM, iʻeliʻia i ka wā o ke kaʻina pucker macular;a me nā maka porcine enucleated, e pili ana i ka hoʻopili ʻana.ʻO ka lōʻihi hawewe lōʻihi o ka absorption o nā mea kala i loko o ka laulā o 527 a 655 nm ma nā ʻano o 0.05%.Ua hōʻike ʻo Rhodamine G6 a me RDB-B3 i nā hopena maikaʻi ʻole ma ka ARPE-19 cell proliferation ma kahi ʻano o 0.2% a ua kāpae ʻia mai ka noiʻi hou ʻana i nā pūnaewele RPE mua.ʻAʻole i hōʻike ʻia ke koena ʻehā i ka hopena ʻawaʻawa i ka ARPE-19 a me ka hoʻonui ʻana o ka cell RPE mua ma nā ʻano o 0.2% a me 0.02%.Ua hoʻopili ʻia ke ola o ka cell e LGSF melemele (0.2%) a me CB (0.2% a me 0.02%).ʻAʻole i hōʻike ʻia nā mea ʻawaʻawa ʻelua (E68 a me BPB) i loko o ka vitro.I loko o kēia noiʻi ʻana ua ʻike ʻia ʻehā mau mea pena me nā hiʻohiʻona hoʻopaʻapaʻa maikaʻi, me ʻelua o kēia mau kala ʻaʻohe hopena ʻona i ʻike ʻia ma nā cell RPE in vitro.
