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Methyl 4-(4-Fluorophenyl)-6-Isopropyl-2-[(N-methyl-N-methylsulfonyl)amino]pyrimidine-5-carboxylate(Z6)CAS: 289042-11-1

ʻO ka wehewehe pōkole:

Ka helu helu: XD93411
Cas: 289042-11-1
ʻAno Molekala: C17H20FN3O4S
Kaumaha Molekala: 381.42
Loaʻa: Loaʻa
Kumukuai:  
Hoʻopili mua:  
Pūʻulu Nui: Noi Manao

 


Huahana Huahana

Huahana Huahana

Helu Helu XD93411
inoa mea kūʻai Methyl 4-(4-Fluorophenyl)-6-Isopropyl-2-[(N-methyl-N-methylsulfonyl)amino]pyrimidine-5-carboxylate(Z6)
CAS 289042-11-1
ʻAno Molekalala C17H20FN3O4S
Kaumaha Molekala 381.42
Nā kikoʻī mālama Ambient

Huahana Huahana

Ka nana aku Pauda keʻokeʻo
ʻO Assay 99% min

 

ʻO Methyl 4-(4-Fluorophenyl) -6-Isopropyl-2- [(N-methyl-N-methylsulfonyl) amino] pyrimidine-5-carboxylate, i ʻike ʻia ʻo Z6, he hui pū me nā mea hiki ke hoʻohana ʻia i ke kahua o nā lāʻau lapaʻau. ʻO ka hiki ʻana o ka hui phenyl i hoʻololi ʻia i ka fluoro i hoʻopili ʻia i ke apo pyrimidine e hōʻike ana e hiki ke launa pū ʻo Z6 me nā pahuhopu olaola, e lilo ia i moho hoʻohiki no ka ʻimi ʻana i ka lāʻau lapaʻau.ʻO ka hoʻohuiʻana o ka hui isopropyl e hoʻonui i ka hydrophobicity o ka pūhui, hiki ke hoʻonui i kona hiki ke komo i nā membrane biological a hiki i ka pae i manaʻoʻia.Hoʻopili ʻia kēia pūʻulu hana me ka hoʻonui ʻana i ke kūpaʻa metabolic o ka pūhui a me ka hōʻemi ʻana i nā hopena o waho.Hiki iā ia ke kōkua i ka hoʻoheheʻe ʻana o ka pūhui i loko o nā kaiapuni polar.Hiki ke waiwai kēia mau waiwai i ka hoʻomohala ʻana i nā pūhui bioactive. ʻO ka loaʻa ʻana o ka hui methyl ester ma Z6 e hāʻawi i kahi ana o ka paʻa a me ka maʻalahi o ka lawelawe ʻana.Eia hou, hiki i ka hui carboxylate ma ke kūlana 5 o ke apo pyrimidine he kahua kūpono no nā hoʻololi kemika, e ʻae ai i nā haʻawina pili pili i ka hana a me ka hoʻonui ʻana i nā waiwai pharmacological. mea hoʻohui (API) no ka mālama ʻana i nā maʻi like ʻole.Hiki ke ʻimi ʻia no kona hiki ʻana ma ke ʻano he anti-inflammatory agent, antiviral drug, a i ʻole i nā lāʻau lapaʻau maʻi kanesa.Hiki i ka hui 'oko'a o nā pū'ulu hana ke hā'awi i nā manawa kūpono no nā pilina olaola koho, e lilo ia i moho u'i no ka modulation target lā'au. Eia kekahi, 'o ka pa'akikī a me ka 'oko'a o Z6 e lilo ia i wahi ho'omaka hoihoi no ke kūkulu 'ana i nā hale waihona puke li'ili'i a i 'ole nā ​​scaffolds kemika.Hiki iā ia ke hana ma ke ʻano he hale kūkulu no ka synthesis o nā derivatives like ʻole, hiki i ka ʻimi ʻana i nā pilina hana-hana a me ka ʻike ʻana i nā pūhui alakaʻi no ka hoʻonui hou ʻana. nā lāʻau lapaʻau like ʻole.ʻO kona hiki ma ke ʻano he API, i hui pū ʻia me ka versatility e hoʻololi ʻia a hoʻomaikaʻi ʻia, hana ia i mea hoʻohui hoihoi no ka ʻike ʻana i ka lāʻau a me nā hana hoʻomohala.Pono nā haʻawina a me nā noiʻi hou aʻe e ʻimi a hoʻohana pono i kona hiki ke hoʻōla.


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    Methyl 4-(4-Fluorophenyl)-6-Isopropyl-2-[(N-methyl-N-methylsulfonyl)amino]pyrimidine-5-carboxylate(Z6)CAS: 289042-11-1