Metronidazole Cas: 443-48-1
| Helu Helu | XD91888 |
| inoa mea kūʻai | ʻO Metronidazole |
| CAS | 443-48-1 |
| ʻAno Molekalala | C6H9N3O3 |
| Kaumaha Molecular | 171.15 |
| Nā kikoʻī mālama | 2-8°C |
| Kānāwai Kūʻai Kūlike | 29332990 |
Huahana Huahana
| Ka nana aku | ʻO ka pauka kristal keʻokeʻo |
| ʻO Assay | 99% min |
| Lae hehee | 159-161 °C (kukui) |
| Lae paila | 301.12°C (manaʻo koʻikoʻi) |
| mānoanoa | 1.3994 (manaʻo koʻikoʻi) |
| hōʻike hoʻopaʻapaʻa | 1.5800 (manaʻo) |
| Fp | 9℃ |
| hikiwawe | ʻakika acetic: 0.1 M, akaka, melemele palupalu |
| pka | pKa 2.62(H2O, t = 25±0.2, ʻAʻole maopopo) (ʻAʻole maopopo) |
| Hiki i ka wai | <0.1 g/100 mL ma 20 ºC |
ʻO Metronidazole ka lāʻau i koho ʻia no nā amebiases, trichomonasis vaginal a me trichlomonadic urethritis i nā kāne, lambliosis, amebic dysentery, a me nā maʻi anaerobic i hoʻokumu ʻia e nā microorganism i maʻalahi i ka lāʻau.ʻO nā inoa like o kēia lāʻau lapaʻau he flagyl, protostat, trichopol, a me vagimid.
Loaʻa ka Metronidazole ma ke ʻano he waha, intravaginal, topical, a me ka hoʻomākaukau makua.Hana ʻia ia e kekahi mau ʻoihana, akā loaʻa wale ma ke kau ʻana.ʻAʻole hiki ke hōʻike ʻia i ke kaiapuni me ka manaʻo ʻole, a inā loaʻa ia, ʻaʻole hiki ke kumu i ka ʻona.
Hoʻohana ʻia ma ke ʻano he antibacterial i ka mālama ʻana i ka rosacea.Antiprotozoal (trichomonas).He mea make kino kanaka.
ʻO Metronidazole, kahi lāʻau antibiotic a antiprotozoal.Hoʻohana nui ʻia e mālama a pale paha i nā maʻi ʻōnaehana a kūloko paha i hana ʻia e nā maʻi anaerobic, e like me nā maʻi bacterial anaerobic i loko o ka ʻōpū o ka ʻōpū, digestive tract, ʻōnaehana hānau wahine, ʻāpana hanu haʻahaʻa, ʻili a me nā ʻiʻo palupalu, iwi a me nā hui, etc. , nā maʻi maningeal, a me ka colitis i hoʻohana ʻia e ka hoʻohana ʻana i ka lāʻau antibiotic.Hoʻohana pinepine ʻia ʻo Tetanus me ka tetanus antitoxin (TAT).Hiki ke hoʻohana ʻia no ka maʻi anaerobic waha.Ma ʻOkakopa 27, 2017, ua hoʻokaʻawale mua ʻia ka papa inoa o nā carcinogens i paʻi ʻia e ka World Health Organization's International Agency for Research on Cancer no ke kuhikuhi ʻana, a ua hoʻokomo ʻia ka metronidazole i ka papa inoa o nā carcinogens papa 2B.I Ianuali 2020, ua koho ʻia ka metronidazole i ka papa ʻelua o ka papa inoa kūʻai lāʻau lapaʻau kūloko.
ʻO Metronidazole ka lāʻau lapaʻau maikaʻi loa i loaʻa no ka mālama ʻana i nā poʻe me nā ʻano ʻano amebiasis a pau, koe wale nō paha ke kanaka asymptomatic akā hoʻomau i ka hoʻokuʻu ʻana i nā ʻōpū.Pono kēlā kūlana i kahi amebicide intraluminal kūpono, e like me ka diloxanide furoate, paromomycin sulfate, a i ʻole diiodohydroxyquin.Hoʻoikaika ka Metronidazole i nā ʻōpū a me nā ʻōpū extraintestinal a me nā trophozoites.
ʻOiai ua hoʻohana ʻia ka quinacrine hydrochloride no ka mālama ʻana i ka giardiasis, makemake nui nā kauka i ka metronidazole.ʻO Furazolidone kahi koho ʻē aʻe.
ʻO Metronidazole ka lāʻau i koho ʻia ma ʻEulopa no nā maʻi bacteria anaerobic;ʻO ka hopohopo e pili ana i ka carcinogenicity hiki ke alakaʻi i kekahi makaʻala i kona hoʻohana ʻana ma ʻAmelika Hui Pū ʻIa. I kēia mau lā ua ʻike ʻia he kūpono i ka mālama ʻana i nā maʻi D. medinensis (Guinea worm) a me Helicobacter pylori.
Hoʻohana ʻia ia i ka maʻi rosacea, balantidiasis a me ka maʻi ilo Guinea.ʻO nā maʻi T. vaginalis kū'ē i ke ʻano maʻamau e pono ai ka mālama kūikawā.
