Nā huahana

ʻO N-[(S)-1-Carbethoxy-1-butyl]-(S)-alanine kahi hui me nā mea hiki ke hoʻohana ʻia ma ke kahua o ka lāʻau lapaʻau a me ka biochemistry.ʻO kāna mau hiʻohiʻona hoʻolālā e lilo ia i moleke hoihoi no nā hoʻohana like ʻole. Aia kēia pūhui i kahi pūʻulu butyl i hoʻopili ʻia i ke kalapona alpha o ka alanine, kahi waikawa amino pono.ʻO ka hele ʻana o ka hui carbethoxy ma ka N-terminus e hoʻohui i kahi hana ester i ka mole.ʻO kēia hui pū ʻana o nā mea hoʻolālā e hāʻawi i nā manawa kūpono no ka hoʻololi ʻana i ka biological a me ke kemika.ʻO ka ʻāpana alanine ka mea i hiki ke kūkulu ʻia i ka synthesis o nā lāʻau lapaʻau peptide.Ua loaʻa i nā peptides ka manaʻo nui i ka ʻoihana lāʻau lapaʻau ma muli o kā lākou hana olaola a me ka kikoʻī kikoʻī.N-[(S)-1-Carbethoxy-1-butyl]-(S)-alanine hiki ke lilo i wahi hoʻomaka no ka synthesis o nā peptide analogs me nā waiwai pharmacological i hoʻonui ʻia. no ka enzymatic a i ʻole kemika hydrolysis, hiki ke hoʻokuʻu i ka ʻāpana alanine i loko o ke kino.Hoʻokomo ʻia ʻo Alanine i nā ala metabolic like ʻole, me ka synthesis protein, ka hana glucose, a me ka metabolism ikehu.No laila, hiki ke ʻimi ʻia nā derivatives N-[(S)-1-Carbethoxy-1-butyl]-(S)-alanine ma ke ʻano he prodrugs hiki ke hoʻokuʻu koho i ka alanine, hiki ke hoʻopilikia i nā kaʻina metabolic i loko o ke kino. ma ke kahua o ka biochemistry a me ka enzymology.ʻO ka hoʻokomo ʻana o ka pūʻulu butyl i ke kaulahao ʻaoʻao alanine e hana i kahi hopena steric i hiki ke hoʻoikaika i ka pilina enzyme-substrate a i ʻole ka pilina protein-protein.He mea waiwai paha kēia i ke aʻo ʻana i nā kinetics enzyme, ka pelu ʻana i ka protein, a me ka launa pū ʻana o ka protein-protein i nā ʻōnaehana olaola. me ka hiki ke ʻimi hou aku a me ka hoʻomohala ʻana i ka noiʻi lāʻau lapaʻau a me ka biochemical.Hāʻawi kona mau hiʻohiʻona i nā manawa kūpono no ka kemika lāʻau lapaʻau, nā haʻawina enzyme, a me ka noiʻi metabolic.Ma ka hoʻohana ʻana i kāna mau waiwai kemika a me ka ʻimi ʻana i kāna mau pilina me nā ʻōnaehana olaola, hiki i nā mea noiʻi ke wehe i nā noi hou a me nā pono kūpono o kēia pūhui ma nā ʻano haʻawina like ʻole. ʻO S)-alanine kahi hui e paʻa ai ka ʻōlelo hoʻohiki no ka noiʻi lāʻau lapaʻau, biochemistry, a me enzymology.ʻO kona ʻano kūʻokoʻa a me nā hana olaola hiki ke wehe i nā mea hiki ke hoʻomohala i nā lāʻau lapaʻau peptide-based, prodrugs, a me ka hoʻokolokolo ʻana i nā kinetics enzyme a me nā pilina protein.ʻO ka ʻimi hou ʻana a me ke aʻo ʻana o kēia pūhui ka mea hiki ke wehe i nā noi hou a kōkua i ka holomua ʻepekema i kēia mau kahua.