Platinum(IV) chloride Cas:13454-96-1 ʻulaʻula ʻulaʻula
Helu Helu | XD90688 |
inoa mea kūʻai | Platinum(IV) chloride |
CAS | 13454-96-1 |
ʻĀpana Molekala | Cl4Pt |
Kaumaha Molecular | 336.89 |
Nā kikoʻī mālama | E mālama ma lalo o +30 ° C |
Kānāwai Kūʻai Kūlike | 28439090 |
Huahana Huahana
Ka nana aku | Pauda ʻulaʻula-ʻulaʻula |
Hoʻāʻo | 99% |
Density | 4.303 |
Lae hehee | 370 ℃ |
logP | 2.75550 |
No ke kūkulu ʻana i kahi mea lawe lāʻau a me ka gene vector PEG-PEI-Pt.Polyethyleneglycol (PEG) i hui pū ʻia me polyethylenimine (PEI 600) a me ka platinum tetrachloride;Ua hoʻokumu ʻia ka paʻakikī PEG-PEI-Pt i ka ethanol.Hōʻike ʻia ka paʻakikī e XRD, UV-VIS a me FT-IR a ua hoʻāʻo ʻia ka condensation DNA e ka electrophoretic mobility shift assay.Ua loiloi ʻia ke ola o ka cell e ka MTT assay ma Hela, B16, A293 a me COS-7 cell a ua ana ʻia ka pono o ka transfection in vitro i nā cell A293 a me B16. ʻO ke ʻano o ka PEG-PEI-Pt i hōʻike ʻia e XRD, UV-VIS a me FT -IR.Ua hiki i ka PEG-PEI-Pt complex ke hoʻopaʻa i ka DNA ma ka ratio kaumaha N / P o 0.4: 1;Ua hōʻike ka paʻakikī i ka cytotoxicity ma nā pūnaewele Hela a me B16.Ua ʻoi aku ka maikaʻi o ka hoʻololi ʻana o ka paʻakikī ma nā pūnaewele A293 a me B16 ma mua o ka PEI 600. Ua kūkulu maikaʻi ʻia kahi mea lawe lāʻau hou a me ka gene vector PEG-PEI-Pt.