Streptavidin mai Streptomyces avidinii CAS:9013-20-1
| Helu Helu | XD90329 |
| inoa mea kūʻai | ʻO Streptavidin mai Streptomyces avidinii |
| CAS | 9013-20-1 |
| ʻĀpana Molekala | C14H17BrClNO2S |
| Kaumaha Molecular | 378.71 |
| Nā kikoʻī mālama | -15 a -20 °C |
| Kānāwai Kūʻai Kūlike | 35040090 |
Huahana Huahana
| Ka nana aku | Pauda keʻokeʻo |
| Hoʻāʻo | 99% |
| No ka noiʻi wale nō, ʻaʻole no ke kanaka | noiʻi wale nō, ʻaʻole no ke kanaka |
Ua hōʻike ʻia ʻo Alkyne-hinged 3-fluorosialyl fluoride (DFSA) i loaʻa i kahi hui alkyne he mea hoʻopaneʻe hiki ʻole ke hoʻololi ʻia o ka sialidases.ʻO ka ester-protected analog DFSA (PDFSA) he membrane-permeable precursor o DFSA i hoʻolālā ʻia e hoʻohana ʻia i loko o nā keena ola, a ua hōʻike ʻia e hana i nā hoʻohui covalent me ka maʻi virus, bacteria, a me nā sialidases kanaka.Hiki ke hoʻopili ʻia ka mea hoʻohui fluorosialyl-enzyme me kahi biotin azide-annexed ma o ka pākuʻi ʻana a ʻike ʻia e nā hōʻailona hōʻike kikoʻī streptavidin.ʻO ka chromatography wai-nui ka nānā ʻana i nā ʻāpana peptide tryptic e hoʻololi ana ka moiety 3-fluorosialyl i nā koena tyrosine o nā sialidases.Ua hoʻohana ʻia ʻo DFSA e hōʻike i ka maʻi maʻi influenza a me ka hōʻoia ʻana o ka maʻi maʻi i ka lāʻau anti-influenza oseltamivir acid, akā ua hoʻohana ʻia ʻo PDFSA no ke kiʻi ma kahi o nā loli o ka hana sialidase i nā cell ola.
