Nā huahana

Pili ʻia ka maʻi maʻi maʻi me ka haʻahaʻa haʻahaʻa a me ke koʻikoʻi oxidative.Bupleurum Polysaccharides (BPs), kaawale mai Bupleurum smithii var.Loaʻa i ka parvifolium nā waiwai anti-inflammatory a me nā anti-oxidative.Eia naʻe, liʻiliʻi ka ʻike e pili ana i kona hopena therapeutic i ka maʻi diabetes.I loko o kēia hoʻokolohua, ua noiʻi ʻia nā hopena o nā BP i ka hoʻohaʻahaʻa ʻana i ka maʻi diabetes a me nā hana kumu.Ua hoʻokumu ʻia ke ʻano ʻiole maʻi maʻi maʻi ma o ka hoʻokō intraperitoneal injection o streptozotocin (100 mg/kg kino kaumaha) no ʻelua lā.Ua koho ʻia nā ʻiole me ke kiʻekiʻe o ka glucose koko ma mua o 16.8mmol/L no nā hoʻokolohua.Hāʻawi waha ʻia nā ʻiole diabetic me BPs (30 a me 60 mg / kg) hoʻokahi i ka lā no 35 mau lā.ʻAʻole i hoʻemi nui nā BP i nā pae o ka glucose koko, akā ua hoʻonui pū i ka nui o ka insulin serum a me ka glycogen ate i nā ʻiole maʻi maʻi i hoʻohālikelike ʻia me nā ʻiole hoʻohālike.Hoʻohui hou, hoʻomaikaʻi ka lawelawe ʻana o BP i ka ʻōlelo insulin a hoʻopaʻa i ka apoptosis i ka pancreas o nā ʻiole maʻi maʻi.Ua hōʻike hou ʻia ka nānā ʻana i ka histopathological i ka pale ʻana o nā BP i ka pancreas a me ka ate mai nā pōʻino oxidative a me nā ʻeha.Hōʻike kēia mau hopena i ka pale ʻana o nā BP i nā pancreatic β cell a me nā hepatocytes ate a me ka hoʻomaikaʻi ʻana i ka maʻi maʻi diabetes, i pili pū me kāna mau waiwai anti-oxidative a me nā anti-inflammatory.