Nā huahana

ʻO Trifluoromethanesulfonic anhydride, i ʻike mau ʻia ʻo triflic anhydride a i ʻole Tf2O, he mea hoʻohana maʻamau i hoʻohana nui ʻia i ka synthesis organik, ʻoi aku ma ke kahua o ke kemika synthetic.ʻO ia kahi pūhui reactive nui e lawelawe ana i nā kumu he nui ma muli o kona ʻakika ikaika a me ka hiki ke hana i nā hopena kemika like ʻole.Hoʻoikaika ikaika ʻo ia me nā waiʻona, e hoʻohuli iā lākou i kā lākou eter e pili ana.Hoʻohana maʻamau ʻia kēia pane ʻana, ʻike ʻia ʻo Williamson ether synthesis, i loko o nā hoʻonohonoho hoʻokolohua a me nā kaʻina hana ʻoihana e hana i nā molekala organik paʻakikī.He mea pono loa ka triflic anhydride no ka hoʻololi ʻana i nā waiʻona i hoʻopaʻa ʻia, ʻaʻole hiki ke hana koke me nā reagents ʻē aʻe, i loko o nā ethers me ka maikaʻi.Hiki ke hoʻohana ʻia no ka pale ʻana i nā pūʻulu hana koʻikoʻi, e like me nā waiʻona a me nā amine, ma ka hana ʻana i nā triflates paʻa.Hiki ke koho ʻia kēia mau triflates ma lalo o nā kūlana kūpono e hana hou i nā pūʻulu hana i makemake ʻia.He waiwai nui kēia hoʻolālā i ka synthesis multi-step, kahi e pono ai ka pale a me ka deprotection o nā pūʻulu hana e hoʻokō i nā hopena i makemake ʻia ma ke ʻano koho.ʻO kona acidity kiʻekiʻe, i loaʻa mai ka trifluoromethanesulfonic acid i hana ʻia ma ke alo o ka wai, e hoʻomaʻamaʻa i nā hopena i hoʻopaʻa ʻia i ka waikawa.Hiki iā ia ke hāpai i nā ʻano hoʻololi like ʻole e like me ka esterifications, acylations, a me ka hoʻonohonoho hou ʻana, e hiki ai i ka synthesis o nā molekala paʻakikī.Hiki iā ia ke hana me nā nucleophiles e hoʻolauna i nā pūʻulu triflyl (CF3SO2), he mau hana maʻamau i ka kemika synthetic.Hana nā hui Triflyl ma ke ʻano he hui haʻalele maikaʻi, e hiki ai i nā hopena hope e like me ka nucleophilic substitutions a rearrangements.Pono e hana i nā hana palekana kūpono, e like me ka hoʻohana ʻana i nā lole pale kūpono, nā mīkina lima, a me nā maka maka, a me ka hana ʻana ma kahi wahi e hoʻomaha maikaʻi ʻia.Hoʻohui ʻia, ma muli o kona ʻano corrosive, ʻōlelo ʻia e mālama i ka triflic anhydride ma lalo o kahi ea inert. nā pūʻulu, kahi catalyst, mea hoʻolaha, a me kahi electrophile.ʻO kāna versatility a me ka reactivity e lilo ia i ʻāpana koʻikoʻi o nā kaʻina hana hoʻokolohua a me nā kaʻina hana ʻenehana, e hiki ai i ka synthesis maikaʻi o nā pūhui organik.Eia nō naʻe, pono e mālama ʻia ka mālama ʻana i ka triflic anhydride, ka mālama ʻana i nā protocols palekana kūpono e hōʻoia i ka maikaʻi o ka chemist a pale i nā pōʻino i loko o ka hale hana.