Nā huahana

ʻO 1-(3-Carboxypyrid-2-yl) -2-phenyl-4-methyl-piperazine, i kapa ʻia ʻo CPPMP, he hui kemika me kahi ʻano paʻakikī i loaʻa nā noi like ʻole i ke kahua o ka lāʻau lapaʻau. o CPPMP i ka mālama ʻana i nā maʻi neurological.ʻO ka loaʻa ʻana o kahi hui carboxypyridyl e hōʻike ana i kona hiki ke launa pū me nā mea loaʻa neuronal kikoʻī i loko o ka ʻōnaehana nerve waena.Hiki i ka ʻimi ʻana i kēia mau mea loaʻa ke hoʻololi i ka neurotransmission, hiki ke alakaʻi i nā hopena therapeutic i nā kūlana e like me ke kaumaha, ka hopohopo, a me nā maʻi neurodegenerative.Pono e noiʻi hou aku e ʻimi i ka pilina o ka mea hoʻokipa kūikawā a me ka hana o ka CPPMP i mea e hoʻonui ai i kona hiki ke lilo i mea lapaʻau no nā maʻi neurological.Hiki i nā lāʻau lapaʻau ke hoʻololi i nā ʻāpana like ʻole o kona ʻano e hoʻomaikaʻi ai i kāna mau waiwai lāʻau lapaʻau a i ʻole ke kuhikuhi ʻana i nā ala olaola kikoʻī.Ma ka hoʻonui ʻana i ka hoʻolālā o CPPMP, hiki i nā mea noiʻi ke hoʻolālā i nā derivatives me ka hoʻomaikaʻi ʻana i ka koho, ka ikaika, a me nā ʻaoʻao palekana, e hoʻolilo iā lākou i mau moho kūpono no nā lāʻau lapaʻau e kuhikuhi ana i nā maʻi like ʻole. nā membrane cell a komo i nā pahuhopu intracellular.Hiki ke hoʻohana ʻia kēia hiʻohiʻona no ka hoʻolālā ʻana i nā lāʻau lapaʻau hou e kuhikuhi pono ana i nā enzyme intracellular a i ʻole nā ​​ala, e hāʻawi ana i nā manawa no ka hana therapeutic i nā maʻi e like me ke kanesa a i ʻole nā ​​maʻi metabolic. .Ma ka hoʻololi ʻana i kāna pūʻulu carboxypyridyl, hiki ke hoʻolālā ʻia ka pūhui i ʻoi aku ka paʻa a i ʻole ka liʻiliʻi o ka ʻawaʻawa i kona ʻano maoli, ʻoiai e hāʻawi maikaʻi ana i ka moiety lāʻau ikaika i ke kahua o ka hana i makemake ʻia.Hiki i ia mau hoʻololi ke hoʻonui i ka bioavailability a me ka therapeutic efficacy o ka mea hoʻohui.Eia kekahi, pono nā hoʻohana a pau o CPPMP e hahai i nā kuʻina palekana a me nā alakaʻi i hoʻopaʻa ʻia e hōʻoia i ka mālama pono ʻana a me ka hōʻemi ʻana i ka hopena. , paʻa i ka ʻōlelo hoʻohiki no nā noi like ʻole i ka lāʻau kemika.Hāʻawi kona ʻano paʻakikī i nā manawa kūpono no ka hoʻomohala ʻana i nā mea lapaʻau hou no nā maʻi neurological, a me nā lāʻau lapaʻau e kuhikuhi ana i nā maʻi like ʻole.Me ka noiʻi hou a me ka hoʻonui ʻana, hiki i ka CPPMP ke hāʻawi i nā haʻawina nui i ke kahua o ka lāʻau lapaʻau a hoʻomaikaʻi i nā hopena maʻi.