Nā huahana

ʻO 2-(Chloromethyl) -4-methylquinazoline kahi mea hoʻohui kemika no ka ʻohana quinazoline.ʻO Quinazolines nā pūhui kūlohelohe me kahi ʻano bicyclic i haku ʻia me kahi apo benzene i hui pū ʻia me kahi apo pyrimidine.Loaʻa i kēia pūhui kikoʻī ka mana nui no ka hoʻohana ʻana i nā noi like ʻole, me nā lāʻau lapaʻau a me nā mea ʻepekema.Loaʻa i nā derivatives Quinazoline nā ʻano hana olaola like ʻole, e ʻoluʻolu iā lākou no ka ʻike ʻana a me ka hoʻomohala ʻana.Ua aʻo ʻia lākou no ko lākou hiki ke mālama i nā maʻi like ʻole, me ka maʻi kanesa, nā maʻi neurological, a me nā maʻi cardiovascular.Ma ke kaohi ʻana i nā ala kikoʻī a i ʻole nā ​​​​protein i manaʻo ʻia e pili ana i ka ulu ʻana a me ke ola ʻana o ka maʻi kanesa, ua hōʻike lākou i ka hiki ke lilo i mau mea lapaʻau kūpono.ʻO ka loaʻa ʻana o kahi hui chloromethyl i 2-(chloromethyl) -4-methylquinazoline hiki ke hoʻonui hou i kona pono, no ka mea, ua hōʻike ʻia nā mea halogen e hoʻomaikaʻi i ka bioactivity a me ke koho ʻana o nā lāʻau lapaʻau. o nā enzymes e pili ana i nā maʻi neurodegenerative, e like me Alzheimer a me Parkinson.Ua hōʻike kēia mau pūhui i ka hiki ke hele i ka pale koko-lolo, e hoʻohiwahiwa ana iā lākou no ka huli ʻana i ka ʻōnaehana nerve waena.ʻO kā lākou ʻano molekala kūʻokoʻa, i hui pū ʻia me ko lākou hiki ke hoʻololi i nā ʻano hoʻololi kemika, e hoʻolilo iā lākou i mau poloka hale no ka synthesis o nā mea hana.Hiki i kēia mau mea ke hōʻike i nā waiwai e like me ka fluorescence, electroconductivity, a me ka molecular recognition, e hoʻohana pono iā lākou i nā wahi e like me optoelectronics, sensing, a catalysis. nā noi.Hiki ke hoʻohana ʻia nā ʻano hana kemika like ʻole, e like me ka hoʻololi ʻana, ka hoʻohui ʻana, a me ka hoʻohui ʻana, e hoʻolauna i nā pūʻulu hana a i ʻole e hoʻololi i ke ʻano kumu.ʻO kēia maʻalahi e hiki ai i nā mea noiʻi ke hoʻolālā a hana i nā derivatives me nā waiwai i hoʻonui ʻia a i ʻole nā ​​​​hana i manaʻo ʻia.ʻO kāna bioactivity, ʻo ia hoʻi i ka maʻi kanesa a me ka noiʻi neuropharmacology, lilo ia i moho hoihoi no ka hoʻomohala ʻana i ka lāʻau lapaʻau.Hoʻohui ʻia, ʻo kāna ʻano hana maʻalahi e lilo ia i poloka hale waiwai no nā mea hana ma nā ʻano āpau.Ke holomua nei ka noiʻi ʻana, e ʻike ʻia nā noiʻi hou aʻe i ka hiki piha a me ka hoʻohana ʻana o kēia pūhui ma nā wahi like ʻole o ka ʻepekema a me ka ʻenehana.