Nā huahana

ʻO ka pūhui 2,4,5-Trifluorobenzyl bromide he mea hoʻohuihui me ke ʻano kemika C7H5BrF3.He pūhui ʻala ia no ka papa o nā derivatives benzyl.Hōʻike ʻia ka pūhui e ka hiki ʻana o ʻekolu mau fluorine i hoʻopili ʻia i ka hui benzyl a me kahi atom bromine.Hiki ke hoʻohana ʻia ma ke ʻano he papa kūkulu hale i ka hoʻomākaukau ʻana i nā mea like ʻole.ʻO ka hui trifluoromethyl i loko o ka pūhui e hāʻawi i ka reactivity kūʻokoʻa a me nā waiwai i hiki ke hoʻohana ʻia no ka synthesis o nā molekala organik paʻakikī.Eia kekahi laʻana, hoʻohana pinepineʻia ka pūhui i ka hanaʻana i nā lāʻau lapaʻau fluorinated, agrochemicals, a me nā mea hana biologically'ē aʻe.Hana ʻia ka bromine atom ma ke ʻano he hui haʻalele a hiki ke hoʻololi i nā hopena kahi i pani ʻia ai ka bromine e nā hui hana ʻē aʻe.Hana kēia waiwai i ka pūhui i mea pono i ka synthesis o nā pūhui like ʻole ma o ka hoʻohana ʻana i ka hui benzyl. Eia kekahi, hiki i ka mea hoʻohui electron-withdrawing fluorine atoms ke hoʻoikaika i ka reactivity a me ke kūpaʻa o nā huahana i loaʻa mai ka 2,4,5-trifluorobenzyl bromide.Hiki i ka hiki ʻana o ka fluorine atoms ke hoʻonui i ka metabolic stability o nā lāʻau lapaʻau a hoʻonui i ka lipophilicity, hiki ke hoʻopili i kā lākou mau waiwai pharmacokinetic, e like me kā lākou absorption a me ka hāʻawi ʻana i ke kino. i nā ʻano hana kemika.No ka laʻana, hiki iā ia ke komo i ka hoʻopili ʻana, e like me Suzuki-Miyaura cross-coupling, e hana i nā paʻa kalapona.Loaʻa kēia hopena i nā noi ākea i ka lāʻau lapaʻau a me ka agrochemical synthesis. I ka hopena, 2,4,5-Trifluorobenzyl bromide he hui versatile me nā noi i ka synthesis organik.ʻO kāna hui trifluoromethyl a me bromine atom e hāʻawi i nā manawa kūpono no ke kūkulu ʻana i nā molekala paʻakikī a me ka hana o ka hui benzyl.ʻO ka hoʻoulu ʻana a me nā waiwai o ka pūhui he mea waiwai ia no ka synthesis o nā lāʻau lapaʻau, agrochemical, a me nā pūhui hana biologically ʻē aʻe.Eia kekahi, hiki iā ia ke lawelawe ma ke ʻano he reagent pono a i ʻole waena ma nā ʻano hopena kemika.