Nā huahana

ʻO ka hui (2S,3R,4S,5S,6R)-2-(3-(4-((S)-tetrahydrofuran-3-yloxy)benzyl)-4-chlorophenyl)-tetrahydro-6-(hydroxymethyl)-2 ʻO -methoxy-2H-pyran-3,4,5-triol he mole mole me nā mea hiki ke hoʻohana ʻia i nā ʻano ʻano like ʻole, me ka lāʻau lapaʻau a me ka lāʻau lapaʻau. me kekahi apo pyran.ʻO ka loaʻa ʻana o nā stereocenters he nui i loko o kona ʻano he mole chiral, ʻo ia hoʻi aia ma nā ʻano enantiomeric ʻelua i hiki ke loaʻa i nā hana olaola like ʻole.ʻO nā hiʻohiʻona hana o ka mole, e like me nā hui benzyl a me chlorophenyl, i hui pū ʻia me ka loaʻa ʻana o nā pūʻulu hydroxyl he nui, e hōʻike ana i ka hana olaola.Hiki i nā mea lāʻau lapaʻau ke ʻimi i ka hiki o ka pūhui ma ke ʻano he hui alakaʻi no ka hoʻomohala ʻana i nā lāʻau hou, ʻoi aku ka nui o nā maʻi e pili ana i ka metabolism carbohydrate. me nā mea loaʻa a i ʻole nā ​​enzyme e pili ana i ka metabolism carbohydrate a i ʻole nā ​​ala hōʻailona.Hiki i nā mea noiʻi ke noiʻi i kona hiki ma ke ʻano he mea pale a modulator paha o nā enzyme kikoʻī a i ʻole nā ​​​​loaʻa i komo i kēia mau kaʻina.Eia kekahi, ʻo ka paʻakikī o ka hoʻokumu ʻana o ka pūhui e lilo ia i moho kūpono no ka loiloi kemika lāʻau ma o ka hoʻololi ʻana.Hiki i nā pūʻulu Hydroxyl ke komo i nā pilina pili hydrogen, e hoʻohuli ana i ka solubility o ka pūhui, kūpaʻa, a me nā waiwai pharmacokinetic.Hiki i nā lāʻau lapaʻau ke hoʻohana i kēia mau pūʻulu e hoʻonui i ka ikaika o ka pūhui, ka koho, a me nā waiwai pharmacological ʻē aʻe. ʻO ka paʻakikī o ka hoʻokumu ʻana o ka pūhui e hōʻike pū ana i ka hoʻohana ʻana i ka ʻepekema waiwai a me ka synthesis organik.Hiki ke hoʻohana ʻia kona hoʻonohonoho kūʻokoʻa o nā pūʻulu hana no ka synthesis o nā pūhui organik hou me nā waiwai kikoʻī a i ʻole nā ​​​​hana.Eia hou, hiki i ka hui ke lilo i wahi hoʻomaka no ka hoʻomohala ʻana i nā mea hou, e like me nā polymers a i ʻole nā ​​hale supramolecular, me nā noi kūpono i nā ʻoihana like ʻole. (3-(4-((S))-tetrahydrofuran-3-yloxy)benzyl)-4-chlorophenyl)-tetrahydro-6-(hydroxymethyl)-2-methoxy-2H-pyran-3,4,5-triol nona ka hale nā hiʻohiʻona e hiki ai ke hoʻohana i ka lāʻau lapaʻau a me ka lāʻau lapaʻau, ʻepekema waiwai, a me ka synthesis organik.ʻO kona ʻano paʻakikī a me nā ʻano hui like ʻole e hāʻawi i nā manawa no ka ʻimi ʻana i ka ʻike ʻana i ka lāʻau lapaʻau, ka modulation enzyme, ka hoʻomohala ʻana i nā mea, a me nā wahi noiʻi ʻē aʻe.