Nā huahana

ʻO 2,3,4,6-Tetrakis-O-trimethylsilyl-D-gluconolactone (TMS-D-glucose lactone) he mea hoʻohui kemika i ʻike ʻia no kāna mau noi i ka synthesis organik, ʻo ia hoʻi ma ke kahua o ka kemika carbohydrate.He kumu ia o D-glucose, he kōpaʻa maoli, a loaʻa iā ia nā waiwai kūʻokoʻa e hoʻohana pono ai i nā hopena kemika like ʻole.Hiki ke loaʻa nā pūʻulu hydroxyl i nā kalapona, e komo pū ana me nā kō, hiki ke hana me nā reagents ʻē aʻe a i ʻole nā ​​​​hoʻololi makemake ʻole i ka wā synthesis.Ma ka pale ʻana i nā pūʻulu hydroxyl kikoʻī me ka hoʻohana ʻana i ka TMS-D-glucose lactone, hiki i ka poʻe kemika ke hoʻomalu i nā hopena hopena a hoʻoponopono pono i nā hale kaʻa.Ma hope o ka pau ʻana o nā hopena i makemake ʻia, hiki ke wehe maʻalahi nā pūʻulu pale, e hōʻike ana i ka huahana i makemake ʻia. ʻIke pū ʻia ʻo TMS-D-glucose lactone i nā noi ma ke ʻano he waena i ka synthesis o nā derivatives carbohydrate paʻakikī.Ma ka hoʻololi koho ʻana i nā pūʻulu hydroxyl o TMS-D-glucose lactone, hiki i nā chemists ke hoʻokomo i kahi ākea o nā pūʻulu hana a i ʻole nā ​​mea pani ʻē aʻe i loko o ka molekele carbohydrate.ʻAe kēia i ka hana ʻana i nā pūhui i hoʻokumu ʻia i ka carbohydrate me nā noi kūpono i nā lāʻau lapaʻau, nā mea hoʻonaninani, a me nā ʻepekema waiwai.ʻO ka Glycosylation kahi hana koʻikoʻi i ka hoʻokumu ʻana i nā mea paʻa glycosidic, he mea nui ia no ke kūkulu ʻana i nā carbohydrates a me glycoconjugates.Hiki ke hoʻololi ʻia ka lactone TMS-D-glucose i mea hāʻawi glycosyl, e hana ana ma ke ʻano he mau kikowaena reactive i ka glycosylation reactions, e hiki ai ke hoʻopili ʻia o nā carbohydrates i nā molekole ʻē aʻe.Ma ke kau ʻana i ka lactone TMS-D-glucose i nā hopena polymerization, hiki i ka poʻe kemika ke hana i nā kaulahao polymer a i ʻole nā ​​​​pūnaewele me nā iwi kuamoʻo.Hiki i kēia mau polymers carbohydrate ke loaʻa nā waiwai kūʻokoʻa a loaʻa paha nā noi ma nā wahi e like me nā ʻōnaehana lawe lāʻau, bioengineering, a me nā biomaterials.Hoʻohana pinepine ʻia a mālama ʻia ma lalo o ka nitrogen a i ʻole argon atmospheres e pale i ka degradation. Ma ka hōʻuluʻulu ʻana, 2,3,4,6-Tetrakis-O-trimethylsilyl-D-gluconolactone (TMS-D-glucose lactone) he mea hoʻohui i hoʻohana nui ʻia i loko. kemika carbohydrate.ʻO kāna mau noi mua e pili ana i ka pale ʻana i ka kemika hui, ka synthesis waena, ka hana hāʻawi glycosyl, a me ka hana ʻana i nā polymers i hoʻokumu ʻia i ka carbohydrate.Ma ka hoʻohana ʻana i ka lactone TMS-D-glucose i kēia mau kaʻina hana, hiki i nā mea kemika ke hoʻokō i ka mana maikaʻi aʻe ma luna o nā hopena carbohydrate a hana i nā derivatives carbohydrate like ʻole me nā noi kūpono ma nā ʻano ʻano like ʻole.