Nā huahana

ʻO 3-tert-Butoxycarbonylphenylboronic acid, ʻike ʻia hoʻi ʻo Boc-Ph-B(OH)₂, he mea hoʻohuihui mea ola no ka papa o nā waikawa boronic.Loaʻa iā ia kahi apo phenyl i pani ʻia me kahi pūʻulu tert-butoxycarbonyl (Boc) a me kahi hui waika boronic (-B(OH)₂).He nui ka hoʻohana ʻana o kēia pūhui i ka synthesis organik, ʻoi loa ma ke kahua o ka lāʻau kemika.Hiki ke hoʻohui ʻia ka pūʻulu Boc i kahi pūʻulu hana amine e pale iā ia mai nā hopena makemake ʻole i ka wā o ka synthesis o nā molekala paʻakikī.Paʻa ka pūʻulu pale Boc ma lalo o nā ʻano hopena like ʻole a hiki ke maʻalahi ke wehe ʻia ma hope me ka hoʻohana ʻana i nā kūlana acidic haʻahaʻa, e ʻae ai i ka deprotection koho o ka hui amine.Hoʻohana kēia waiwai i ka 3-tert-Butoxycarbonylphenylboronic acid i mea waiwai nui i ka synthesis o peptides, pharmaceuticals, a me nā huahana kūlohelohe.Hiki i ka hui waika boronic ke hana i ka hopena me kekahi ʻano organometallic, ʻo ia hoʻi he aryl a alkyl boronate, ka hopena i ka hoʻokumu ʻana i kahi paʻa kalapona-carbon.Hoʻohana nui ʻia kēia pane no ka hoʻokumu ʻana i nā hale molekala paʻakikī a hoʻokomo i nā pūʻulu aryl a i ʻole alkyl ma luna o kahi mole.ʻO 3-tert-Butoxycarbonylphenylboronic acid, me kāna hui hoʻomalu Boc, hiki ke koho i nā hopena hoʻohui i nā wahi kikoʻī i loko o kahi mole, e hoʻonui ai i ka versatility synthetic a me ka pono.ʻO nā waikawa Boronic, me ka phenylboronic acid derivatives, ua hōʻike i nā hana olaola like ʻole, e like me ka anticancer, antiviral, a me nā waiwai antifungal.Hiki ke hoʻohana ʻia ka hiki o ka 3-tert-Butoxycarbonylphenylboronic acid ke komo i ka hoʻohui ʻana i ke keʻa e hoʻolālā a hoʻohui i nā pūhui hou me nā hana olaola i hoʻonui ʻia.Ua ʻimi nā mea noiʻi i ka synthesis o ka waika boronic derivatives o 3-tert-Butoxycarbonylphenylboronic acid a loiloi i kā lākou pharmacological hiki. nā pane.ʻO kāna ʻano kemika kūʻokoʻa a me ka reactivity e lilo ia i mea waiwai nui no ka synthesis o nā molekala paʻakikī, me nā peptides a me nā lāʻau lapaʻau.Hoʻohui ʻia, ʻo ka hoʻohana ʻana i ka lāʻau lapaʻau o 3-tert-Butoxycarbonylphenylboronic acid a me kāna mau derivatives e lilo ia i mea hoihoi no ka ʻimi hou ʻana i ka lāʻau kemika.