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4-(4-Fluorophenyl)-6-Isopropyl-2-[(N-Methyl-N-Methylsulfonyl)Amino]Pyrimidinyl-5-Yl-Formyl, ʻike ʻia hoʻi ʻo FIMPA, he hui kemika me kahi ʻano paʻakikī i loaʻa ka hiki. noi i ka noiʻi lāʻau lapaʻau a me ka hoʻomohala lāʻau.Hoʻokaʻawale ʻia ʻo ia ma ke ʻano he pyrimidine derivative me kahi hui formyl i hoʻopili ʻia i ka 5th carbon atom, a me ka 4-fluorophenyl a me kahi hui isopropyl i hoʻopili ʻia i ka 4th a me 6th carbon atoms, kēlā me kēia. noiʻi maʻi maʻi.Ua aʻo nui ʻia nā derivatives Pyrimidine no ko lākou mau waiwai antitumor, a hōʻike ʻo FIMPA i ka hiki ke lilo i mea anticancer.ʻO kāna mau hiʻohiʻona hoʻolālā e lilo ia i moho hoʻohiki no ka pale ʻana i nā enzymes nui a i ʻole nā ​​​​mea hoʻokipa e pili ana i ka ulu ʻana a me ka holomua.Hiki i nā mea noiʻi ke hoʻololi hou i ka hoʻolālā o FIMPA e hoʻonui i kona ikaika, koho, a me nā waiwai pharmacokinetic no ka mālama ʻana i ka maʻi maʻi ʻoi aku ka maikaʻi.Hiki i kona hoʻolālā kūʻokoʻa ke hoʻopili i nā pūʻulu hana like ʻole, hiki ke hana koʻikoʻi i ka launa pū ʻana me nā pahuhopu molekala.ʻO kēia versatility ka FIMPA i mea waiwai nui i ka lāʻau lapaʻau no ka hoʻomohala ʻana i nā mea lapaʻau hou e kūʻē i nā maʻi like ʻole e like me nā maʻi neurological a i ʻole nā ​​​​maʻi infectious.Hiki i kona mau pūʻulu hana hoʻokō, e like me nā pūʻulu formyl a me sulfonyl, ke lilo i mau wahi no ka hoʻololi hou ʻana i nā kemika.Hiki i nā mea noiʻi ke hoʻohana i ka FIMPA ma ke ʻano he mea hoʻomaka a i ʻole ka hui waena no ke komo ʻana i nā derivatives like ʻole, hiki ke nānā ʻia no kā lākou mau hana olaola a i ʻole hoʻohana ʻia e like me ke kūkulu hale no ka hoʻohui ʻana o nā molekala paʻakikī. -2-[(N-Methyl-N-Methylsulfonyl)Amino]Pyrimidinyl-5-Yl-Formyl (FIMPA) hōʻike i nā mea hiki ke hoʻohiki i nā wahi like ʻole o ka noiʻi lāʻau lapaʻau a me ka hoʻomohala lāʻau.ʻO kāna hana kūikawā a me nā hui hana e lilo ia i mea hana koʻikoʻi no ka hoʻolālā ʻana i nā moho lāʻau lapaʻau hou a i ʻole synthesizing i nā pūhui organik paʻakikī.ʻO ka ʻimi hou ʻana a me ka hoʻonui ʻana i nā waiwai o FIMPA hiki ke alakaʻi i ka loaʻa ʻana o nā mea lapaʻau noʻonoʻo hou a kōkua i nā holomua i ke kula o ka lāʻau lapaʻau.