4-Amino-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-hoʻokahi Cas:951-77-9
| Ka helu helu: | XD90580 |
| Cas: | 951-77-9 |
| ʻAno Molekala: | C9H13N3O4 |
| Kaumaha Molekala: | 227.22 |
| Loaʻa: | Loaʻa |
| Kumukuai: | |
| Hoʻopili mua: | 1g USD10 |
| Pūʻulu Nui: | Noi Manao |
Huahana Huahana
| Ka nana aku | ʻO ka pauka kristal keʻokeʻo |
| Hoʻāʻo | 99% |
| Lae hehee | 196°C - 200°C |
Ua ʻike ʻo Thymidine phosphorylase (TP, EC 2.4.2.4) i ke ʻano o ka substrate me ka kikoʻī kiʻekiʻe, ma o ke kumu a me ka ribosyl moieties.ʻO ka hoʻololi ʻana o 3'-OH o thymidine i hoʻoikaika nui i kāna hana catalytic me TP.ʻAʻole maikaʻi ka hoʻololi ʻana o nā nucleosides pyrimidine me nā moieties base i hoʻololi ʻia i ke ʻano 1-phosphate.Ua emi iho ka hana o ka hui ha'alele me ka ho'onui 'ana i ka aromaticity o ka pyrimidine base moiety, no ka nui o ka pa'akikī i ka ho'opololei 'ana i ke kumu e nā amino acids kūloko i ka pae hana.ʻO ka hoʻololi ʻana o nā pūʻulu hana 3' a me 5' ua hoʻemi i ka helu pane a me ka hoʻololi pākēneka me TP.He mea nui ka ribosyl 3' hydroxyl pūʻulu no ka hoʻopaʻa ʻana i ka substrate e ka enzyme.Ua hōʻike maopopo ke kinetic assay i nā waiwai K(m) a me V(max) haʻahaʻa i ka hoʻololi ʻana i ka hui hydroxyl 3' me ka hydrogen.
