I ka ʻimi mau ʻana i ka lāʻau antidiabetic palekana a maikaʻi hoʻi, lilo nā algae moana i kumu nui e hāʻawi ai i nā pūhui o ka hiki ke hoʻōla nui.ʻIke ʻia ka alpha-amylase, alpha-glucosidase inhibitors, a me nā pūhui antioxidant no ka mālama ʻana i ka maʻi maʻi maʻi a ua loaʻa ka manaʻo nui i kēia manawa.Ma ka haʻawina o kēia manawa, ua koho ʻia ʻehā mau limu ʻōmaʻomaʻo (Chaetomorpha aerea, Enteromorpha intestinalis, Chlorodesmis, a me Cladophora rupestris) e loiloi i ka alpha-amylase, alpha-glucosidase inhibitory, a me ka hana antioxidant in vitro. .Ua loiloi ʻia ka hana antidiabetic e ka hiki ke pale ʻia o nā extracts e kūʻē i ka alpha-amylase a me ka alpha-glucosidase e nā spectrophotometric assays.Hoʻoholo ʻia ka hana Antioxidant e 2,2-diphenyl-1-picrylhydrazyl, hydrogen peroxide (H2O2), a me ka nitric oxide scavenging assay.Ua lawe ʻia ka loiloi chromatography-mass spectrometry (GC-MS) no ka hoʻoholo ʻana i ka pūhui nui e pili ana i kāna hana antidiabetic. (IC50 - 147.6 μg/ml) hōʻike i ka pale ʻana i ka alpha-amylase.Ua loiloi pū ʻia nā extracts no ka alpha-glucosidase inhibition, a ʻaʻohe hana i ʻike ʻia.Ua hōʻike ʻo Methanol extract o C. rupestris i ka hana scavenging radical manuahi (IC50 - 666.3 μg/ml), a ukali ʻia e H2O2 (34%) a me ka nitric oxide (49%).Eia hou, ua hōʻike ʻia ka hoʻopiʻi kemika e GC-MS i ka loaʻa ʻana o nā pūhui bioactive nui.Phenol, 2,4-bis (1,1-dimethylethyl) a me z, z-6,28-heptatriactontadien-2-one i loaʻa nui i loko o ka methanol extract o C. rupestris a me chloroform extract o C. aerea. e hōʻike ana nā algae i koho ʻia i ka hana hoʻopale alpha-amylase a me ka hana antioxidant.No laila, e noʻonoʻo ʻia ke ʻano o nā pūhui hana a me kāna mau in vivo assays. Ua koho ʻia nā ʻehā ʻōmaʻomaʻo e loiloi i ka alpha-amylase, alpha-glucosidase inhibitory, a me ka hana antioxidant in vitro C. aerea a me Chlorodesmis i hōʻike i ka pale nui ʻana i ka alpha-amylase, a C. rupestris hōʻike i kaulana free radical scavenging activityAʻole i ʻike ʻia he hana kūʻē i ka alpha-glucosidaseGC-MS ka nānā ʻana o nā extracts ikaika e hōʻike ana i ka loaʻa ʻana o nā pūhui nui e hāʻawi i ka ʻike i ka hana antidiabetic a me ka hana antioxidant o kēia mau algae.Hoʻohana ʻia nā pōkole: DPPH: 2,2-diphenyl-1-picrylhydrazyl, BHT: Butylated hydroxytoluene, GC-MS: Gas chromatography-mass spectrometry.
