Nā huahana

ʻO 4''-Propyl-3-fluorobiphenyl-4-boronic acid, i ʻike ʻia ʻo (4-propyl-3-fluorophenyl) boronic acid, he pūhui kemika i loaʻa i ka hoʻohana nui ʻana i nā kula like ʻole, me ka synthesis organik, ʻepekema waiwai, a me ka noiʻi lāʻau lapaʻau. ʻO kekahi o nā noi mua o 4''-Propyl-3-fluorobiphenyl-4-boronic acid i loko o ka hoʻololi metala-catalyzed coupling reactions.Hiki i kēia pūhui ke hana ma ke ʻano he boronic acid kūkulu hale, e ʻae ai i ka hoʻokumu ʻana i nā paʻa kalapona-carbon a i ʻole carbon-heteroatom.No ka laʻana, hiki ke hoʻohana ʻia ma Suzuki-Miyaura cross-coupling reactions, kahi e hana ai me ka aryl a i ʻole vinyl halides ma lalo o ka palladium catalysis e hana i nā pūhui biaryl.Hoʻohana nui ʻia kēia mau hopena hoʻohui keʻa i ka synthesis o nā molekala organik paʻakikī, me nā lāʻau lapaʻau, agrochemical, a me nā mea. hāʻawi i nā manawa kūikawā no ka hoʻomohala ʻana i nā mea hana.Hiki i ka hoʻololi ʻana i ka fluorine ke loaʻa i ka hopena koʻikoʻi i nā waiwai physicochemical o kahi mole, e like me kona hāʻawi uila a me ka hydrophobicity.Hoʻohana kēia mau waiwai i nā derivatives o 4''-Propyl-3-fluorobiphenyl-4-boronic acid i mea pono i nā noi like ʻole, e like me nā kristal wai, OLEDs (organic light-emitting diodes), a me nā mea uila ʻē aʻe. Eia kekahi, ʻo ka hui propyl i ka ʻO ka hoʻolālā o 4''-Propyl-3-fluorobiphenyl-4-boronic acid e hiki ai i ka derivatization maʻalahi, e hāʻawi i ke komo i kahi ākea o nā derivatives hana.Hāʻawi kēia maʻalahi i ka synthesis o nā pūhui like ʻole me nā waiwai a me nā hana kūpono.Hiki ke hoʻololi hou a hoʻohui ʻia kēia mau derivatives i loko o nā molecular frameworks nui e hana i nā hale kūlohelohe paʻakikī, nā moleke bioactive, a me nā mea holomua. nā moho kūpono no ka ʻike ʻana i ka lāʻau.Hōʻike pinepine nā pūhui Fluorinated i ka hoʻomaikaʻi ʻana i ka metabolic stability, hoʻonui i ka lipophilicity, a me ka hoʻololi ʻana i ka hana olaola i hoʻohālikelike ʻia me kā lākou mau mea like ʻole i fluorinated.No laila, hiki i ka hoʻokomo ʻana o ka fluorine atom i loko o nā molekala ʻoihana biologically hiki ke hoʻonui i kā lākou mau waiwai pharmacological, e like me ka potency a me ka koho. , ʻepekema waiwai, a me ka noiʻi lāʻau lapaʻau.ʻO kona hiki ke komo i ka hoʻololi metala-catalyzed coupling reactions, nā waiwai kūʻokoʻa e pili ana me ka fluorine substitution, a me ka hiki no ka derivatization lilo ia i mea waiwai nui no ka hana ʻana i nā molekala organik paʻakikī, nā mea hana, a me nā moho lāʻau lapaʻau.