Nā huahana

ʻO 5-(Difluoromethoxy)-2-mercapto-1H-benzimidazole he mea hoʻohui kemika e paʻa ana i ka mana nui i nā noi lāʻau lapaʻau.Aia kēia pūhui i ka papa o benzimidazole derivatives, i ʻike ʻia no kā lākou mau hana lāʻau lapaʻau.Ua hōʻike nā derivatives Benzimidazole i nā hopena cytotoxic e kūʻē i nā laina cell cancer ma ke kāohi ʻana i ka ulu ʻana o nā cell a me ka hoʻoulu ʻana i ka apoptosis.ʻO nā hoʻololi molekala kūikawā ma 5-(Difluoromethoxy)-2-mercapto-1H-benzimidazole e hoʻonui i kāna hana anticancer, hiki ke wehe i nā puka no nā koho lapaʻau hou i ka oncology.Ua hōʻike nā derivatives Benzimidazole i ka hana antimicrobial maikaʻi e kūʻē i kahi ākea o nā microorganisms, me ka bacteria, fungi, a me nā parasites.Hāʻawi nā hiʻohiʻona kūikawā o kēia pūhui i kona hiki ke antimicrobial, e lilo ia i moho hoʻohiki no ka hakakā ʻana i nā pathogens kū'ē i ka lāʻau lapaʻau a me nā maʻi infectious.He kuleana koʻikoʻi ka inflammatory i ka pathogenesis o nā maʻi like ʻole, me nā maʻi maʻi e like me ka rheumatoid arthritis a me ka maʻi ʻeha o ka ʻōpū.ʻO nā waiwai anti-inflammatory o ka pūhui e lilo ia i mea koho no ka hoʻomohala ʻana i nā lāʻau lapaʻau hou no ia mau kūlana.Ua hōʻike kekahi mau pūhui i kēia papa i nā hopena neuroprotective a me ka hiki ke hoʻonui i ka hoʻomanaʻo a me nā hana cognitive.Hiki i ka 5-(Difluoromethoxy)-2-mercapto-1H-benzimidazole ke hōʻike i nā hopena like, e lilo ia i mea koho no ka hoʻomohala ʻana i nā lāʻau lapaʻau no nā maʻi neurodegenerative e like me nā maʻi o Alzheimer a me Parkinson. 5-(Difluoromethoxy)-2-mercapto-1H-benzimidazole ke hoʻomau ʻia nei ka noiʻi ʻana, a pono e noiʻi hou ʻia e hoʻoholo i kona hiki ke hoʻoponopono piha, palekana, a me nā noi kūpono.He mea koʻikoʻi ia no kekahi hui lāʻau lapaʻau e hana i nā hoʻokolohua koʻikoʻi, me nā hoʻokolohua preclinical a me nā hoʻokolohua lapaʻau, e hoʻokumu i kona pono a me ka ʻike palekana. , dosing, a me nā hopena ʻaoʻao o kekahi pūhui lāʻau.