Nā huahana

ʻO 8-Bromo-3-methyl-xanthine, ka mea i ʻike ʻia ʻo 8-BMX, he pūhui synthetic no ka hui o xanthines.ʻO Xanthines kahi papa o nā pūhui e like me ka caffeine a loaʻa nā hopena like i ke kino.Eia naʻe, ʻaʻole i hoʻohana maʻamau ʻia ka 8-BMX a i ʻike ʻia paha i ka hoʻohālikelike ʻia me nā xanthine ʻē aʻe e like me ka caffeine a i ʻole theophylline.ʻO Adenosine kahi hui kūlohelohe i loko o ke kino e hana ana ma ke ʻano he neuromodulator a hoʻokani i kahi hana i nā kaʻina physiological like ʻole, me ka hoʻoponopono ʻana i ka hiamoe, ka mumū, a me ka hana cardiovascular.Ma ka pale ʻana i nā mea hoʻokipa adenosine, hiki i ka 8-BMX ke hoʻololi i kēia mau kaʻina hana a hāʻawi i nā mea noiʻi me nā ʻike waiwai i ke kuleana o ka adenosine i nā ʻōnaehana like ʻole. ʻōnaehana.Ua hoʻohana ʻia i ka noiʻi e pili ana i ka hopohopo, ke kaumaha, a me nā maʻi neurodegenerative e like me Parkinson's a me Alzheimer's.Ma ka pale ʻana i nā mea loaʻa adenosine, hiki i ka 8-BMX ke hoʻololi i ka neurotransmission a loaʻa paha nā hopena therapeutic i kēia mau kūlana.Eia naʻe, pono e hoʻomaopopo ʻia ʻo ka hoʻohana ʻana o 8-BMX i kēia mau haʻawina he hoʻokolohua nui a ʻaʻole i unuhi ʻia i ka hoʻohana lapaʻau ākea. .No ka laʻana, ua hoʻohana ʻia ma ke ʻano he mea hana e aʻo ai i ka hana o nā adenosine receptors i ka hana cardiorespiratory a me ka noiʻi ʻana i nā hopena o nā antagonists adenosine receptor ma ka puʻuwai a me nā māmā.Eia hou, ua noiʻi ʻia ʻo 8-BMX no kona hiki ke hoʻololi i ka pane ʻana o ka immune a me ka hōʻemi ʻana i ka mumū.Ma ke ʻano he pūhui synthetic, ʻaʻole hiki ke kūʻai ʻia no ka hoʻohana maʻamau a ʻai paha.I loko o ka ʻoihana lāʻau lapaʻau, hoʻohana pinepine ʻia nā xanthine e like me ka caffeine a i ʻole theophylline ma muli o kā lākou ʻike palekana i hoʻokumu ʻia a me nā hopena kaulana. i ka noiʻi ʻepekema ma ke ʻano he antagonist koho o nā adenosine receptors.Ua aʻo ʻia ʻo ia no kāna mau hopena kūpono i ka ʻōnaehana nūnū waena, ka hana cardiovascular, a me ka mumū.Eia nō naʻe, ua kaupalena ʻia kāna mau hana ma waho o nā hoʻonohonoho noiʻi, a ʻo nā xanthine ʻē aʻe e like me ka caffeine i hoʻohana nui ʻia a ʻike ʻia.