Nā huahana

ʻO ka Ethyl 3-amino-4,4,4-trifluorocrotonate kahi hui e loaʻa ai ka noi ma nā wahi like ʻole me ka synthesis organik, kemika lāʻau lapaʻau, a me ka ʻepekema waiwai. he poloka hale ma ka hoʻohui ʻana.Loaʻa iā ia kahi pūʻulu amine a me kahi paʻa pālua, kahi e hoʻolilo ai ia i kahua maʻalahi no ka hana ʻana i nā molekala paʻakikī.Hiki ke hoʻohana ʻia ka hui amino me nā reagents like ʻole e hoʻolauna i kahi ākea o nā hana, ʻoiai ʻo ka paʻa pālua e ʻae ai i nā hoʻololi hou aʻe.Hoʻohana pinepine ʻia kēia pūhui i ka synthesis o nā lāʻau lapaʻau, agrochemical, a me nā mea ʻē aʻe biologically active.ʻIke ʻia ka pūʻulu trifluoromethyl e hoʻonui i ka ikaika a me ke kūpaʻa metabolic o nā lāʻau lapaʻau, e lilo ia i mea hoʻololi hoihoi i ka hoʻolālā lāʻau.Ua hoʻohana ʻia kēia pūhui i ka synthesis o nā inhibitors e kuhikuhi ana i nā enzymes a me nā mea loaʻa, me nā kinases, proteases, a me G protein-coupled receptors.Hāʻawi kāna hui trifluoromethyl kūʻokoʻa i nā waiwai i makemake ʻia i nā mea i loaʻa, e like me ka hoʻonui ʻana i ka lipophilicity, hoʻomaikaʻi i ka hiki ke hoʻihoʻi electron, a me ka hoʻololi ʻana i ka molecular packing.ʻO kēia ka mea e pono ai i ka hoʻomohala ʻana i nā mea hana, e like me nā polymers, nā kristal wai, a me nā mea hoʻonaninani.He ʻāpana koʻikoʻi ka pūʻulu trifluoromethyl i loko o nā molekala organik ma muli o kāna mau hopena maikaʻi i ka physicochemical a me nā waiwai olaola.Hiki i ka pūhui ke hoʻololi i nā kemika like ʻole, e like me ka nucleophilic substitution, oxidation, a me ka hoʻohaʻahaʻa, e hiki ai i ka hoʻokomo ʻana a i ʻole ka hoʻololi ʻana o nā hui fluorinated. i ka hoʻohui ʻana i ka organik, kemika lāʻau lapaʻau, a me ka ʻepekema waiwai.ʻO kona hiki ke lawelawe ma ke ʻano he hale kūkulu hale, me kāna hui trifluoromethyl kū hoʻokahi, lilo ia i mea koʻikoʻi i ka hoʻomohala ʻana i nā lāʻau lapaʻau like ʻole, nā mea waiwai, a me nā pūhui fluorinated.