Nā huahana

ʻO ka Ethyl trifluoropyruvate (ETFP) kahi pūhui kemika e loaʻa ai nā noi ma nā wahi like ʻole, me ka synthesis organik, ka noiʻi lāʻau lapaʻau, a me ka hoʻomohala ʻana i ka agrochemical.Loaʻa ia mai ka pyruvic acid, me ʻekolu mau ʻātoma fluorine (-F) i hoʻopili ʻia i ke kalapona e pili ana i ka hui carboxyl a me kahi hui ethyl (-C2H5) i hoʻopili ʻia i ke kalapona kalapona. hoʻo·hui kino.He waiwai nui ka hui trifluoromethyl i loko o ka ETFP no ka mea, hāʻawi ʻo ia i nā waiwai kemika kū hoʻokahi a makemake ʻia i nā pūhui i hoʻohui ʻia i loko.Hiki i ka hui trifluoromethyl ke hoʻololi i ka reactivity, solubility, a me ka hana olaola, e lilo ia i mea waiwai nui no nā mea lapaʻau lapaʻau a me nā mea hoʻomeaola synthetic.ʻO ka hiki ʻana o ka hui ethyl hiki ke hoʻololi hou i nā molekala, hiki ke hoʻokomo i nā pūʻulu hana like ʻole a hoʻonui i ka versatility holoʻokoʻa o ka pūhui.ʻO ka synthesis o Etflurane e pili ana i ka hopena o ETFP me ka hydrogen fluoride a me ka trifluoroacetic acid e hana i ka huahana hope.ʻO ka hana kū hoʻokahi o ka hui trifluoromethyl ma ETFP e ʻae i ka hoʻokomo koho ʻana i nā ʻātoma fluorine i loko o ka mole Etflurane, e hāʻawi ana i kāna mau mea anesthetic.Hiki i ka hui trifluoromethyl ma ETFP ke hoʻoikaika nui i ka hana olaola o kēia mau pūhui.Ma ka hoʻokomo ʻana i ka pūʻulu trifluoromethyl i loko o ka mole, hiki i nā chemists ke hoʻololi i ka lipophilicity o ka pūhui, metabolic stability, a me ka hoʻopaʻa ʻana i ka pilina i nā enzymes a i ʻole nā ​​​​mea loaʻa i loko o nā mea kanu.ʻAe kēia hoʻololi i ka hoʻolālā ʻana i nā herbicide ʻoi aku ka maikaʻi a me ke koho ʻana i hiki ke hoʻomalu i ka ulu ʻana o ka mea kanu a i ʻole ke kuhikuhi ʻana i nā nāhelehele kikoʻī me ka ʻole e hōʻino i nā mea kanu i makemake ʻia. nā pūhui lāʻau like ʻole.Hiki i ka hui trifluoromethyl ma ETFP ke hoʻonui i ka waiwai pharmacokinetic o ka moho lāʻau, e alakaʻi ana i ka bioavailability, metabolic stability, a me ka pilina paʻa i nā protein target.Hiki i kēia hoʻololi ke hoʻololi i ka ikaika o ka lāʻau, ke koho ʻana, a me ka hiki ke hoʻomaʻamaʻa holoʻokoʻa. E like me kekahi hui kemika, pono e hahai ʻia ka mālama pono ʻana a me ka palekana i ka wā e hana ai me ETFP.Pono e hoʻohana i nā lako pale pilikino kūpono, e like me nā mīkina lima a me nā maka aniani, a e hana ma kahi wahi e hoʻomaha maikaʻi ʻia.Pono e mālama ʻia ʻo ETFP ma kahi maloʻo maloʻo, mamao mai ka wela a me ka lapalapa ʻana.ʻO kāna mau trifluoromethyl a me nā pūʻulu ethyl e hoʻolilo iā ia i poloka hale ākea no ka hoʻololi ʻana i nā hale kemika a hoʻonui i nā waiwai o nā molekala.Mai ka hoʻohui ʻana o ka anesthetics a hiki i ka hoʻomohala ʻana i nā herbicides a me nā lāʻau lapaʻau, lawelawe ʻo ETFP ma ke ʻano he mea waiwai nui no ka poʻe chemists i nā ʻano hana like ʻole.Ma ka hoʻomau ʻana i ka ʻimi ʻana i kāna hana a me nā waiwai, hiki i nā mea noiʻi ke wehe i nā hoʻohana hou a kōkua i nā holomua i nā ʻano ʻepekema like ʻole.