Nā huahana

Ua hōʻike ʻia ka hahau ischemic i ka hypermetabolism o ka glucose i ka penumbra ischemic.Hōʻike ka ʻikepili hoʻokolohua a me ka ʻike lapaʻau ʻo ka hyperglycemia systemic pili i ka infarct he hopena lapaʻau kūpono i ka hahau ʻana.Eia nō naʻe, ʻaʻole i hoʻomaikaʻi maikaʻi ʻia nā hopena hana a i ʻole i hōʻemi ʻia ka make ʻana o nā haʻawina haukaʻi e manaʻo ana i ka hoʻokele glucose i ka hahau ʻana.No laila, pono nā haʻawina hou aku e pili ana i ka metabolism glucose i loko o ka lolo ischemic.Ua kālailai ʻia nā holoholona e [2-(18)F]-2-fluoro-2-deoxy-d-glucose positron emission tomography a i ʻole ke kiʻi kiʻi magnetic i ka wā o 90 mau minuke occlusion o ke aʻa cerebral waena a ma 60 mau minuke ma hope o ka reperfusion.Ua hoʻopili ʻia nā hopena i ke kiʻi hoʻohālikelike magnetic o ke kahe koko cerebral, diffusion o ka wai, ka hoʻokumu ʻana o ka lactate, a me ka ʻikepili histological e pili ana i ka make cell a me ka haki ʻana o ke koko-lolo. -Deoxy-d-glucose ka lawe ʻana i loko o nā ʻāpana ischemic e hāʻule ana i ka infarction a ma ka ʻāina peri-infarct.Ua hōʻike ʻia ke kiʻi hoʻonaʻauao magnetic i ka hōʻemi ʻana o ke kahe o ke koko i nā pae ischemic i loko o ka infarct a me ka hōʻemi ʻana o ke kahe koko cerebral ma ka ʻāina peri-infarct.Hōʻike ʻia ka spectroscopy resonance magnetic i ka lactate i ka ʻāina ischemic a me ka nele o ka lactate i ka ʻāina peri-infarct.Ua hōʻike ʻia nā loiloi immunohistochemical i ka apoptosis a me ka haki ʻana o ke koko-lolo i loko o ka infarct. pono o ke kino lolo ischemic a me ka hypoperfused, a aia ia ma lalo o nā kūlana anaerobic a me ka aerobic i ana ʻia e ka hana lactate kūloko.Hiki ke lawelawe i ka hyperglycemia systemic pili i ka infarct no ka hoʻolako ʻana i ka glucose i ka lolo ischemic.Hiki i ka mālama ʻana i ka glycemic me ka mālama ʻana i ka insulin ke hoʻopilikia maikaʻi ʻole i kēia mīkini.