Iodoacetamide Cas: 144-48-9 98% Keʻokeʻo a melemele paʻa
| Helu Helu | XD90247 |
| inoa mea kūʻai | Iodoacetamide |
| CAS | 144-48-9 |
| ʻĀpana Molekala | C2H4INO |
| Kaumaha Molecular | 184.96 |
| Nā kikoʻī mālama | Ambient |
| Kānāwai Kūʻai Kūlike | 29241900 |
Huahana Huahana
| Nalo ma ka maloo | <1% |
| Hoʻāʻo | ≥98% |
| Nitrogen | 7.2 - 7.8% |
| Ka nana aku | Paʻa keʻokeʻo a melemele |
| Solubility i ka methanol | Aneane akaka |
| Kaona Kaona | 12.5 - 13.2% |
ʻO ka α-Iodoacetamide kahi hui i hoʻohana ʻia ma ke ʻano he electrophile no ka hoʻololi covalent o nā koena nucleophilic ma nā protein (cysteine, methionine, histidine).I ka hoʻololi ʻana i nā koena wahi hana o nā protease cysteine, hana ʻo α-Iodoacetamide ma ke ʻano he mea paʻa ʻole o kēia mau enzymes.
Hoʻohana: Hiki ke hoʻohana ʻia ma ke ʻano he protease inhibitor CH2ICONH2.E like me ka ʻakika iodoacetic, hiki iā ia ke pale i nā enzymes SH ma o kēia mau hopena.R-SH+ICH2CONH2→RS-CH2CONH2+HI
Hoʻohana: Alkylation reagents no ka histidine a me ka cysteine i loko o nā proteomics, no ka peptide sequencing a me ka enzyme inhibitors.Hoʻohana pū ʻia i ka synthesis organik.
