Nā huahana

ʻO ka hyperkalemia i ka wā o ka renin-angiotensin-aldosterone system inhibition (RAAS-I) hiki ke pale i ka hoʻohana ʻana.ʻO nā koho lapaʻau e pili ana i ka sodium polystyrene sulfonate potassium binding resins, akā aia nā pilikia palekana a me ka pono, e pili ana i ka colonic necrosis (CN).Ua aʻo ʻia nā mea ʻokoʻa ʻē aʻe, akā ʻaʻole i manaʻo ʻia ka uku-pono. a i ʻole he resin paʻa "lāʻau X" no ka hyperkalemia mau.Loaʻa ka ʻikepili mai nā palapala e kū nei.Ua hoʻohana mākou i kahi hoʻohālike hoʻoholo hoʻoholo me Monte Carlo probabilistic sensitivity analyses, mai kahi hiʻohiʻona o ka uku mālama olakino a me kahi 12 mau mahina.Ua ana ʻia nā kumukūʻai ma ke kālā ʻAmelika.Ua ana 'ia ka pono ma na makahiki ola i hooponopono i ka maikai (QALYs), a me na ratio hoonui kumu kuai (ICER). WTP) paepae o $ 50,000/QALY.Ma ka $ 40.00 no kēlā me kēia lā, ua loaʻa i ka lāʻau X ka lākiō hoʻonui kumu kūʻai o $26,088,369.00 no ka QALY i loaʻa.Ua hōʻike ʻia ka nānā ʻana o ka naʻau o ka sodium polystyrene sulfonate i ke kumu kūʻai kūpono no nā hanana CN ≤ 19.9%.Loaʻa i nā palena ka ʻike piha ʻole e pili ana i nā hopena o ka maʻi ma waho a me ka nele o ka ʻikepili e hoʻohālikelike pololei ana i ka sodium polystyrene sulfonate i nā mea ʻē aʻe.Hiki ke alakaʻi kēia ʻano loiloi i nā hoʻoholo e pili ana i ka lawe ʻana i nā mea hana ʻē aʻe no ka mālama ʻana i ka hyperkalemia maʻi, a manaʻo e hoʻohana ʻia ka sodium polystyrene sulfonate ma ke ʻano he mana ikaika i nā hoʻokolohua lapaʻau o kēia mau mea hana.