Nā huahana

(S)-(+)-2-Chlorophenylglycine methyl ester hydrochloride he hui me ke kinikini C9H12ClNO2·HCl.He paʻakai ia i hana ʻia e ka hopena o (S)-(+)-2-Chlorophenylglycine methyl ester me ka waikawa hydrochloric.Hoʻohana pinepine ʻia kēia pūhui ma ke kahua o ka chemistry pharmaceutical. ʻO kekahi o nā noi mua o (S)-(+)-2-Chlorophenylglycine methyl ester hydrochloride ma ke ʻano he papa hale chiral i ka synthesis o nā lāʻau lapaʻau like ʻole.ʻO nā pūhui Chiral nā molekole i loaʻa i nā ʻano kiʻi aniani ʻelua, i kapa ʻia ʻo enantiomers.ʻO nā pūhui maʻemaʻe enantiomerically, e like me (S)-(+)-2-Chlorophenylglycine methyl ester hydrochloride, he mea koʻikoʻi i ka ʻoihana lāʻau lapaʻau no ka mea hiki iā lākou ke koho koho me nā pahuhopu olaola kikoʻī, e hoʻonui i ka mana a me ka hōʻemi ʻana i nā hopena ʻaoʻao o nā lāʻau. o ka chlorophenylglycine moiety ma (S)-(+)-2-Chlorophenylglycine methyl ester hydrochloride hāʻawi i ka manawa kūpono no ka synthesis o nā ʻano lāʻau lapaʻau like ʻole.No ka laʻana, hiki ke hoʻohana ʻia ma ke ʻano he precursor i ka synthesis o nā nonsteroidal anti-inflammatory drugs (NSAIDs), antimicrobial agents, a me nā pūhui bioactive ʻē aʻe.Hiki ke hoʻololi i nā mea kiko'ī i hoʻopiliʻia i ka chlorophenylglycine core e hoʻololi i nā mea olaola o nā pūhui i loaʻa.Hiki ke hoʻohana ʻia i nā syntheses multistep e hoʻolauna i ka chirality i nā moho lāʻau lapaʻau like ʻole.Ma ka hoʻokomoʻana i kēia pūhui i loko o ka synthesis, hiki i nā mea lapaʻau lāʻau ke hoʻomalu i ka stereochemistry o ka mole i loaʻa, e hoʻonui i kāna hana olaola a me ke kiko'ī. a me ka waiho ʻana o ka hui.Hoʻohui hou, hiki i ka paʻakai hydrochloride ke hoʻonui i ka solubility o ka pūhui i loko o nā wai wai, e maʻalahi i ka mālama ʻana i nā hopena synthetic like ʻole. ʻO nā noi i ka synthesis o nā pūhui lāʻau lapaʻau, hiki ke ʻokoʻa kona hoʻohana kikoʻī a me ka hopena ma muli o ka molekele i makemake ʻia a me nā kūlana pane.Pono e mālama ʻia ka pūhui me ka mālama, e pili ana i nā protocol palekana kūpono a me nā alakaʻi i ka wā o kāna synthesis a hoʻohana.