Nā huahana

ʻO S-(+)-Methyl-(2-chlorophenyl)[(2-(2-thienyl)amino] acetate hydrochloride, i ʻike ʻia hoʻi ʻo S-(+)-Clopidogrel, he hui lāʻau lapaʻau me kahi ʻano kemika o C16H16ClNO2S·HCl He mea ia o ka clopidogrel, he lāʻau antiplatelet koʻikoʻi. ʻO ka hoʻohana mua ʻana o S-(+)-Methyl-(2-chlorophenyl) [(2-(2-thienyl)amino] acetate hydrochloride he mea hana ikaika. i loko o ka hoʻokumu ʻana i nā lāʻau lapaʻau cardiovascular, ʻo ia hoʻi nā mea antiplatelet. Hoʻohana ia i kāna hopena therapeutic ma ke kāohi ʻana i ka platelet aggregation, ka pale ʻana i ka hoʻokumu ʻana o nā clots koko, a me ka hōʻemi ʻana i ka hopena o nā hanana cardiovascular. ʻO ke kuleana koʻikoʻi i ka hoʻoulu ʻana a me ka hōʻuluʻulu ʻana o nā platelets. Ma ka hoʻopaʻa ʻole ʻana i kēia mea hoʻokipa, S-(+)-Methyl-(2-chlorophenyl)[(2-(2-thienyl)amino] acetate hydrochloride ke kāohi i ka hoʻoulu ʻana o ka platelet a pale i ka hoʻokumu ʻana. ʻO kēia ʻano hana he lāʻau koʻikoʻi ia no ka pale ʻana i nā hanana thrombotic i nā poʻe maʻi i pilikia nui, e like me ka poʻe me ka moʻolelo o ka maʻi maʻi coronary acute, ischemic stroke, a i ʻole ka maʻi aʻa peripheral.S-(+)-Methyl- (2-chlorophenyl)[(2-(2-thienyl)amino] acetate hydrochloride e lawelawe mau ʻia ma ka waha ma ke ʻano o nā papa a i ʻole nā ​​capsules.Ma hope o ka ʻai ʻana, e hoʻololi ʻia ka metabolic i loko o ke ake e hana i kāna metabolite ikaika.Hoʻopaʻa paʻa ʻole kēia metabolite ikaika i ka receptor P2Y12, e hoʻohana ana i kāna mau hopena antiplatelet no kahi lōʻihi.Hoʻonohonoho ʻia ka pūhui i hoʻokahi manawa i kēlā me kēia lā, ma ke ʻano he lāʻau kūʻokoʻa a i hui pū ʻia me nā lāʻau antiplatelet ʻē aʻe, e like me ka aspirin. -thienyl)amino] acetate hydrochloride pono e hoʻohana wale ʻia ma lalo o ke alakaʻi ʻana a ke kauka mālama ola kino, no ka mea hiki ke hoʻohana ʻia.