Tetracycline hydrochloride CAS:64-75-5 99% Ka pauda crystalline melemele
| Helu Helu | XD90366 |
| inoa mea kūʻai | Tetracycline hydrochloride |
| CAS | 64-75-5 |
| ʻĀpana Molekala | C22H24N2O8 · HCl |
| Kaumaha Molecular | 480.90 |
| Nā kikoʻī mālama | -15 a -20 °C |
| Kānāwai Kūʻai Kūlike | 29413000 |
Huahana Huahana
| Ka hopena | Kūlike me BP2013, EP7, USP38 |
| Nā metala kaumaha | <0.005% |
| Hoʻokahi haumia | <0.1% |
| ʻIkepili | IR, UV, HPLC, TLC |
| pH | 1.8-2.8 |
| Nalo ma ka maloo | <2.0% |
| Ke koena solvent | n-Butanol <3000ppm |
| Hoʻāʻo | BP2013/EP7 99% |
| Lehu Sulphated | <0.5% |
| ʻO ka hoʻololi ʻana i ka optical kikoʻī | -240 a i -255° |
| Ka mana | USP 38: >900ug/mg |
| Huina paumaele | <5% |
| Ka nana aku | Ka pauda kristal melemele |
| 4-epianhydrotetracycline | <2% |
| Nā palena microbial | Hoʻokō |
| 4-Epiteracycline | <3% |
| Anhydrotetracyoline | <0.5% |
| ʻO Chlortetracycline Hydrochloride | <0.5% |
| Koena Solvent | <100ppm |
Hoʻonui ʻia ka hoʻomohala ʻana o ka pale antimicrobial i ka hoʻohana ʻole ʻana i nā lāʻau antimicrobial.ʻO Staphylococci kekahi ʻāpana o ka flora maʻamau akā he mau pathogens hiki ke lilo i mea kūʻokoʻa i nā lāʻau antibiotic i ʻike ʻia.Manaʻo ʻia e ulu aʻe nā kūʻē i ka coagulase negative staphylococci (CoNS) ma muli o ke kaomi koho maikaʻi ma hope o ka mālama ʻana i ka lāʻau antibiotic.Ua noiʻi kēia haʻawina i ka loaʻa ʻana o nā mea antimicrobial ʻeiwa i hoʻohana pinepine ʻia i loko o ka mimi kanaka mai nā maʻi maʻi ma nā halemai ʻelua ma Ghana e pili ana i ke kū'ē ʻana o CoNS.Ua hoʻohālikelike ʻia ka Urine a me CoNS (n = 246 a me n = 96) mai nā maʻi ma nā halemai ʻelua ma Ghana.Ua ʻike ʻia ʻo CoNS me ka hoʻohana ʻana i ka Gram staining, coagulase test, a me MALDI-TOF/MS, a ua hoʻoholo ʻia ka maʻalahi o ka antimicrobial i 12 antimicrobial i hoʻohana mau ʻia e ka diffusion disk.Eia kekahi, ua hoʻomohala ʻia kahi ʻano analytical no ka hoʻoholo ʻana i nā mea ʻeiwa i hoʻohana pinepine ʻia ma Ghana ma o ka hoʻohana ʻana i ka solid-ph ase extraction me ka HPLC-MS/MS me ka hoʻohana ʻana i ka electron spray ionization.Ua ʻike ʻia ke alapine kiʻekiʻe o ke kū'ē ʻana iā CoNS no ka penicillin V (98%), trimethoprim (67%), a me ka tetracycline (63%).ʻO S. haemolyticus ka mea hoʻokaʻawale maʻamau (75%), a ma hope o S. epidermidis (13%) a me S. hominis (6%).ʻO S. haemolyticus nō hoʻi ka ʻano e hōʻike ana i ka maʻi kūʻē kiʻekiʻe loa (82%).ʻO 69% o nā CoNS i hoʻokaʻawale ʻia he mau lāʻau kūʻokoʻa (≧ 4 mau lāʻau antibiotic) a ʻo 45% o ka ConS he methicillin kūʻē.Ua ʻike ʻia nā lāʻau antimicrobial ma 64% o nā ʻano mimi i kālailai ʻia (n = 121) kahi i ʻike pinepine ʻia ai nā antimicrobials ciprofloxacin (30%), trimethoprim (27%), a me metronidazole (17%).ʻO nā mea nui o kēia noiʻi ʻana, ʻo ka nui o nā antimicrobials i ʻike ʻia i loko o ka mimi ua ʻoi aku ka pinepine ma mua o ka hoʻohana ʻana i hōʻike ʻia e nā maʻi a ʻoi aku ka pinepine o ka S. haemolyticus kūpaʻa ma mua o nā ʻano CoNS kūʻokoʻa i ka wā i ʻike ʻia ai nā mea antimicrobial i loko o ka mimi.
